FCER1A

Gene Symbol	FCER1A
Entrez Gene	2205
Alt Symbol	FCE1A, FcERI
Species	Human
Gene Type	protein-coding
Description	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Other Description	Fc IgE receptor, alpha polypeptide|Fc epsilon RI alpha-chain|Fc-epsilon RI-alpha|high affinity immunoglobulin epsilon receptor alpha-subunit|high affinity immunoglobulin epsilon receptor subunit alpha|igE Fc receptor subunit alpha|immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
Swissprots	P12319
Accessions	AAA16115 BAB84120 CAA01564 CAA82702 CAN36268 EAW52789 P12319 BC005912 AAH05912 BC015185 BC015195 AAH15195 DQ893131 ABM84057 DQ896411 ABM87410 DQ896467 ABM87466 J03605 AAA36204 X06948 CAA30025 NM_002001 NP_001992
Function	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Top Pathways	Fc epsilon RI signaling pathway, Asthma, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Fc ε RIα siRNA (h) - sc-45258 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Fc ε RIα shRNA Plasmid (h) - sc-45258-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Fc ε RIα shRNA (h) Lentiviral Particles - sc-45258-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Fc epsilon RI RNAi - H00002205-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Fc epsilon RI RNAi - H00002205-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU014371 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8581 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8581 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02517 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02517

FCER1A siRNA (Human) - CRH1540 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FCER1A - MBS8200560 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human FCER1A (NM_002001.3) - SHH293621 from Creative biogene Category siRNA Species Reactivities Human

Human FCER1A siRNA - orb262042 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FCER1A shRNA Plasmid (Human) - CHH1540 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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