KCNH1

Gene Symbol KCNH1
Entrez Gene 3756
Alt Symbol EAG, EAG1, Kv10.1, TMBTS, h-eag
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated eag related subfamily H, member 1
Other Description EAG channel 1|ether-a-go-go potassium channel 1|ether-a-go-go, Drosophila, homolog of|hEAG1|potassium voltage-gated channel subfamily H member 1|potassium voltage-gated channel, subfamily H (eag-related), member 1|voltage-gated potassium channel subunit Kv10.1
Swissprots O76035 Q14CL3 O95259 B1AQ26
Accessions CCQ43886 EAW93424 EAW93425 O95259 AF078741 AAC68668 AF078742 AAC68669 AJ001366 CAA04700 AK127526 BC113709 AAI13710 BC143599 AAI43600 XM_011509514 XP_011507816 NM_002238 NP_002229 NM_172362 NP_758872
Function Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel (PubMed:22732247). Channel properties may be modulated by subunit assembly, but not by cyclic nucleotides (By similarity). Mediates IK(NI) current in myoblasts (PubMed:9738473). Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (PubMed:23881642). {ECO:0000250|UniProtKB:Q60603, ECO:0000269|PubMed:22732247, ECO:0000269|PubMed:23881642, ECO:0000269|PubMed:9738473}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21559285, ECO:0000269|PubMed:22732247, ECO:0000269|PubMed:22841712}; Multi- pass membrane protein {ECO:0000269|PubMed:21559285}. Nucleus inner membrane {ECO:0000269|PubMed:21559285}; Multi-pass membrane protein {ECO:0000269|PubMed:21559285}. Early endosome membrane {ECO:0000269|PubMed:22841712}. Note=Perinuclear KCNH1 is located to NPC-free islands.
Tissue Specificity Highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.

Human KCNH1 protein fragment - ab116850 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE stained with Coomassie Blue showing ab116850 at approximately 36.52 kDa.

Recombinant Human KCNH1 Protein - H00003756-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

KCNH1 peptide - orb217510 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Zebrafish

KCNH1 - H00003756-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

KCNH1 - H00003756-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

KCNH1 fusion protein - Ag16647 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

KCNH1 fusion protein - Ag17430 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human KCNH1 - KCNH1-29891TH from Creative Biomart

Category Protein
Source Wheat germ
Species Human

Kv10.1 Blocking Peptide - CBP1647 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Zebrafish

KV10.1 Peptide - BS5772P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Potassium voltage-gated channel subfamily H member 1 (KCNH1), Recombinant Protein - MBS1033401 from MyBioSource

Category Protein
Prices $1,375.00, $1,835.00
Sizes 1 mg (E-Coli), 1 mg (Yeast)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

KCNH1 Recombinant Protein Antigen - NBP1-84935PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

KCNH1 Peptide, Human - M34GP07948H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Eag protein (eag), Recombinant Protein - MBS1071893 from MyBioSource

Category Protein
Prices $785.00, $785.00, $1,010.00, $1,010.00, $1,095.00, $1,095.00, $1,555.00, $1,555.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Bacteriophage
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