Gene Symbol |
Adrb3
|
Entrez Gene |
11556
|
Alt Symbol |
Adrb-3
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
adrenergic receptor, beta 3
|
Other Description |
Beta-3 AR|Beta-3 adrenoceptor|beta 3-AR|beta-3 adrenergic receptor|beta-3 adrenoreceptor|beta3-adrenergic receptor
|
Swissprots |
Q9QZ98 P25962 A2RS74
|
Accessions |
CAA42966 CAA51384 EDL32791 P25962 AF193027 AAF05768 AK136495 BAE23009 AK143775 BAE25534 BC132000 AAI32001 JQ692584 AFG28505 S53290 AAB24836 XM_006508987 XP_006509050 XM_006508988 XP_006509051 XM_011242116 XP_011240418 XM_011242117 XP_011240419 NM_013462 NP_038490
|
Function |
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
White and brown adipose tissues, and digestive tract. Isoform B highest in brain.
|
Top Pathways |
Calcium signaling pathway, Endocytosis, Salivary secretion, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction
|