| Gene Symbol | Adrb3 |
|---|---|
| Entrez Gene | 11556 |
| Alt Symbol | Adrb-3 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | adrenergic receptor, beta 3 |
| Other Description | Beta-3 AR|Beta-3 adrenoceptor|beta 3-AR|beta-3 adrenergic receptor|beta-3 adrenoreceptor|beta3-adrenergic receptor |
| Swissprots | Q9QZ98 P25962 A2RS74 |
| Accessions | CAA42966 CAA51384 EDL32791 P25962 AF193027 AAF05768 AK136495 BAE23009 AK143775 BAE25534 BC132000 AAI32001 JQ692584 AFG28505 S53290 AAB24836 XM_006508987 XP_006509050 XM_006508988 XP_006509051 XM_011242116 XP_011240418 XM_011242117 XP_011240419 NM_013462 NP_038490 |
| Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | White and brown adipose tissues, and digestive tract. Isoform B highest in brain. |
| Top Pathways | Calcium signaling pathway, Endocytosis, Salivary secretion, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction |
β 3 -AR siRNA (m) - sc-39869 from Santa Cruz Biotechnology
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β 3 -AR shRNA Plasmid (m) - sc-39869-SH from Santa Cruz Biotechnology
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β 3 -AR shRNA (m) Lentiviral Particles - sc-39869-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN26361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26361 from Sigma-Aldrich
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ADRB3 siRNA (Mouse) - CRM0091 from Cohesion Biosciences
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ADRB3 - MBS8239715 from MyBioSource
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shRNA set against Mouse Adrb3(NM_013462.3) - SHG044107 from Creative biogene
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Mouse ADRB3 siRNA - orb279567 from Biorbyt
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ADRB3 shRNA Plasmid (Mouse) - CHM0091 from Cohesion Biosciences
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ADRB3 miRNA 3'UTR clone - MiUTR1M-01265 from Creative biogene
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