Notch4

Gene Symbol Notch4
Entrez Gene 18132
Alt Symbol Int-3, Int3, N4
Species Mouse
Gene Type protein-coding
Description notch 4
Other Description Notch gene homolog 4|neurogenic locus notch homolog protein 4
Swissprots Q62389 Q9R1X0 Q9R1W9 O88316 Q62390 O35442 P31695 O88314
Accessions AAB82004 CAM18615 EDL26808 EDL26809 EDL26810 EDL26811 EDL26812 P31695 AK143484 AK166261 AK166493 BC138044 AAI38045 BC145114 M80456 AAB38377 XM_006523798 XP_006523861 XM_006525349 XP_006525412 XR_385298 XR_385939 NM_010929 NP_035059
Function Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May regulate branching morphogenesis in the developing vascular system. {ECO:0000250, ECO:0000269|PubMed:11344305}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in lung, moderately in heart kidney, and at lower levels in the ovary and skeletal muscle. A very low expression is seen in the brain, intestine, liver and testis.
Top Pathways Notch signaling pathway, MicroRNAs in cancer, Dorso-ventral axis formation

Notch 4 (C-3) - sc-377399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Notch 4 (C-3): sc-377399. Western blot analysis of Notch 4 expression in mouse kidney tissue extract.

Notch 4 (E-11) - sc-32634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Notch 4 (E-11): sc-32634. Western blot analysis of Notch 4 expression in 293T whole cell lysate.

Notch 4 (L-16) - sc-8645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Notch 4 (L-16): sc-8645. Western blot analysis of Notch 4 expression in mouse kidney tissue extract.

Notch 4 (M-18) - sc-32636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Notch 4 (M-19) - sc-8646 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Notch 4 (M-19): sc-8646. Western blot analysis of Notch 4 expression in 293T whole cell lysate.

Anti-NOTCH4 antibody [HMN4-14] (Phycoerythrin) - ab95776 from Abcam

Prices $376.00
Sizes 100 µg
Clonality Monoclonal
Clone HMN4-14
Flow cytometric analysis of CD8+CD11c+ C57BL/6 splenocytes with 0.25 µg of Armenian Hamster IgG Isotype Control PE (blue histogram) or ab95776 at 0.5 µg (purple histogram). Total viable cells were used for analysis.

Notch-4 Antibody (HMN4-14) [PE] - NBP2-00270 from Novus Biologicals

Host Hamster
Clonality Monoclonal
Clone HMN4-14

Hamster ANTI NOTCH 4 Antibody (OASA11463) - OASA11463 from Aviva Systems Biology

Prices $345.00
Sizes 250 µg
Host Hamster
Clonality Monoclonal
Clone HMN4-14

Hamster ANTI NOTCH 4 Antibody (OASA11464) - OASA11464 from Aviva Systems Biology

Prices $160.00
Sizes 100 µg
Host Hamster
Clonality Monoclonal
Clone HMN4-14

NOTCH4 antibody [HMN4-14] - GTX39541 from GeneTex

Prices $199.00
Sizes 100 μg
Host Hamster
Clonality Monoclonal
Clone HMN4-14

NOTCH4 antibody [HMN4-14] - GTX39542 from GeneTex

Prices $319.00
Sizes 250 μg
Host Hamster
Clonality Monoclonal
Clone HMN4-14

Notch4 Antibody (APC) [out of stock] - abx016809 from Abbexa

Host Mouse
Clonality Monoclonal

Notch4 Antibody (Biotin) [out of stock] - abx016807 from Abbexa

Host Mouse
Clonality Monoclonal

Notch4 Antibody (FITC) [out of stock] - abx016806 from Abbexa

Host Mouse
Clonality Monoclonal

Notch4 Antibody (PE) [out of stock] - abx016808 from Abbexa

Host Mouse
Clonality Monoclonal

Notch4 Antibody [out of stock] - abx016810 from Abbexa

Host Mouse
Clonality Monoclonal

Alexa Fluor® 647 anti-mouse Notch 4 Antibody - 128412 from Biolegend

Prices $295.00
Sizes 100 µg
Host Hamster
Clone HMN4-14
FN4/CHO (mouse Notch-4) transfected cell line stained with HMN4-14 Alexa Fluor® 647

APC anti-mouse Notch 4 Antibody - 128413 from Biolegend

Prices $135.00
Sizes 25 µg
Host Hamster
Clone HMN4-14
FN4/CHO (mouse Notch-4) transfected cell line stained with HMN4-14 APC

Biotin anti-mouse Notch 4 Antibody - 128404 from Biolegend

Clone HMN4-14
Mouse Notch 4 transfected CHO cells were stained with biotinylated Notch 4 (clone HMN4-14) (filled histogram) or Armenian hamster IgG(open histogram), followed by Sav-APC.

PE anti-mouse Notch 4 Antibody - 128407 from Biolegend

Prices $150.00
Sizes 50 µg
Host Hamster
Clone HMN4-14
FN4/CHO (mouse Notch-4 transfected) cells stained with HMN4-14 PE

Anti-NOTCH4 antibody - STJ72523 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

Mouse NOTCH 4 Antibody - GWB-Q00792 from Genway Biotech

Prices $168.00
Sizes 100 µg
Host Hamster

Mouse NOTCH 4 Antibody - GWB-Q00791 from Genway Biotech

Prices $363.00
Sizes 250 µg
Host Hamster

NOTCH 4, Monoclonal Antibody - MBS224370 from MyBioSource

Prices $565.00
Sizes 100 tests
Host Hamster
Clonality Monoclonal
Clone HMN4-14

NOTCH 4, Monoclonal Antibody - MBS219857 from MyBioSource

Prices $355.00
Sizes 250 µg
Host Hamster
Clonality Monoclonal
Clone HMN4-14
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