Notch4

Gene Symbol Notch4
Entrez Gene 18132
Alt Symbol Int-3, Int3, N4
Species Mouse
Gene Type protein-coding
Description notch 4
Other Description Notch gene homolog 4|neurogenic locus notch homolog protein 4
Swissprots Q62389 Q9R1X0 Q9R1W9 O88316 Q62390 O35442 P31695 O88314
Accessions AAB82004 CAM18615 EDL26808 EDL26809 EDL26810 EDL26811 EDL26812 P31695 AK143484 AK166261 AK166493 BC138044 AAI38045 BC145114 M80456 AAB38377 XM_006523798 XP_006523861 XM_006525349 XP_006525412 XR_385298 XR_385939 NM_010929 NP_035059
Function Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May regulate branching morphogenesis in the developing vascular system. {ECO:0000250, ECO:0000269|PubMed:11344305}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in lung, moderately in heart kidney, and at lower levels in the ovary and skeletal muscle. A very low expression is seen in the brain, intestine, liver and testis.
Top Pathways Notch signaling pathway, MicroRNAs in cancer, Dorso-ventral axis formation

Neurogenic locus notch homolog protein 4, Notch4, Mouse, ELISA Kit - E2421m from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t

Neurogenic locus notch homolog protein 4, NOTCH4, ELISA Kit - MBS9307069 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neurogenic locus notch homolog protein 4, NOTCH4, ELISA Kit - MBS9306306 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Notch4 ELISA Kit - E061382 from Biobool

Category ELISA Kit

NOTCH4 ELISA Kit (Mouse) (OKEH05162) - OKEH05162 from Aviva Systems Biology

Category ELISA Kit
Prices $440.00
Sizes 96 wells
Sensitivity 0.078 ng/mL
Range 0.156-10 ng/mL

Neurogenic locus notch homolog protein 4, ELISA Kit - MBS2886403 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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