MBD4

Gene Symbol MBD4
Entrez Gene 8930
Alt Symbol MED1
Species Human
Gene Type protein-coding
Description methyl-CpG binding domain protein 4
Other Description 3,N(4)-ethenocytosine glycosylase|G/5-fluorouracil mismatch glycosylase with biphasic kinetics|G/T mismatch glycosylase|G/U mismatch glycosylase|methyl-CpG-binding domain protein 4|methyl-CpG-binding endonuclease 1|methyl-CpG-binding protein MBD4|mismatch-specific DNA N-glycosylase|putative methyl-CpG binding protein
Swissprots Q96F09 Q2MD36 D3DNC3 O95243 D3DNC4 B4DZN2 E9PEE4 Q7Z4T3
Accessions AAD50374 AAM00008 EAW79251 EAW79252 EAW79253 EAW79254 EAW79255 O95243 AF072250 AAC68879 AF114784 AAD22195 AF532602 AAP97338 AK303013 BAG64144 AK312878 AM180876 CAJ55826 BC011752 AAH11752 BC034463 BP370521 BY997577 CD678412 CR450305 CAG29301 DB568237 JF432222 ADZ15439 XM_011513267 XP_011511569 XM_011513268 XP_011511570 NM_001276270 NP_001263199 NM_001276271 NP_001263200 NM_001276272 NP_001263201 NM_001276273 NP_001263202 NM_003925 NP_003916
Function Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. {ECO:0000269|PubMed:10097147, ECO:0000269|PubMed:10930409}.
Subcellular Location Nucleus.
Top Pathways Base excision repair

MBD4 CRISPR/Cas9 KO Plasmid (h) - sc-403156 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 HDR Plasmid (h) - sc-403156-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 Double Nickase Plasmid (h) - sc-403156-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 Double Nickase Plasmid (h2) - sc-403156-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 CRISPR Activation Plasmid (h) - sc-403156-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 CRISPR Activation Plasmid (h2) - sc-403156-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 Lentiviral Activation Particles (h) - sc-403156-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 Lentiviral Activation Particles (h2) - sc-403156-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD4 siRNA (h) - sc-37763 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBD4 shRNA Plasmid (h) - sc-37763-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBD4 shRNA (h) Lentiviral Particles - sc-37763-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU025861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13078 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13078 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05103 from Sigma-Aldrich

Category miRNA

MBD4 siRNA (Human) - CRH5905 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MBD4 RNAi - H00008930-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MBD4 (NM_003925.1) - SHH338799 from Creative biogene

Category siRNA
Species Reactivities Human

Human MBD4 siRNA - orb266407 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MBD4 shRNA Plasmid (Human) - CHH5905 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MBD4 miRNA 3'UTR clone - MiUTR1H-06133 from Creative biogene

Species Reactivities Human
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