NKX6-1

Gene Symbol NKX6-1
Entrez Gene 4825
Alt Symbol NKX6.1, NKX6A
Species Human
Gene Type protein-coding
Description NK6 homeobox 1
Other Description NK homeo box, family 6, member A|NK homeobox, family 6, A|NK6 transcription factor homolog A|NK6 transcription factor related, locus 1|homeobox protein NK-6 homolog A|homeobox protein Nkx-6.1
Swissprots P78426
Accessions AAD11962 EAX05949 P78426 BC160030 AAI60030 XM_006714230 XP_006714293 NM_006168 NP_006159
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Pancreatic beta cells.
Top Pathways Maturity onset diabetes of the young

Nkx-6.1 (C-14) - sc-15030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nkx-6.1 (C-14): sc-15030. Western blot analysis of Nkx-6.1 expression in rat pancreas tissue extract.

Nkx-6.1 (N-15) - sc-15027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nkx-6.1 Antibody (N-15): sc-15027. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing nuclear and cytoplasmic staining of exocrine glandular cells and Islets of Langerhans.

Nkx-6.1 (5B8) - sc-130385 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Nkx-6.1 (5B8): sc-130385. Western blot analysis of Nkx-6.1 expression in HL-60 whole cell lysate.

Anti-nkx6.1 antibody - ab129659 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-nkx6.1 antibody (ab129659) at 1/100 dilution + A549 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-nkx6.1 antibody - ab90706 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-nkx6.1 antibody (ab90706) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal small intestine lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-nkx6.1 antibody - ab123412 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-nkx6.1 antibody (ab123412) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-nkx6.1 antibody - C-terminal - ab199906 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-nkx6.1 antibody - C-terminal (ab199906) at 1/1000 dilutionLane 1 : Mouse brain total cell extractsLane 2 : Mouse thymus total cell extracts

Anti-NKX6-1 Antibody (aa1-120) - LS-C124275 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa50-200, DY650) - LS-C143536 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa50-200, Biotin) - LS-C143535 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa50-200, HRP) - LS-C143538 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa1-120) - LS-C144076 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-NKX6-1 Antibody (aa50-200, DY550) - LS-C143539 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa50-200, DY488) - LS-C143537 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa284-312, APC) - LS-C215994 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa284-312, AP) - LS-C215995 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa284-312, FITC) - LS-C215996 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa284-312, PE) - LS-C215997 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa285-314, AP) - LS-C215998 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa285-314, APC) - LS-C215999 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa50-200) - LS-C143534 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Nkx6.1 Antibody - IHC staining of Nkx6.1 in mouse intestine.

Anti-NKX6-1 Antibody (N-Terminus) - LS-C109702 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NKX6-1 antibody LS-C109702 Western blot of Fetal Small Intestine lysate.

Anti-NKX6-1 Antibody (clone 1B7) - LS-C197787 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B7
NKX6-1 monoclonal antibody (M01), clone 1B7 Western Blot analysis of NKX6-1 expression in HL-60.

Anti-NKX6-1 Antibody (aa285-314, FITC) - LS-C216000 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX6-1 Antibody (aa285-314, PE) - LS-C216001 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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