NKX6-1

Gene Symbol NKX6-1
Entrez Gene 4825
Alt Symbol NKX6.1, NKX6A
Species Human
Gene Type protein-coding
Description NK6 homeobox 1
Other Description NK homeo box, family 6, member A|NK homeobox, family 6, A|NK6 transcription factor homolog A|NK6 transcription factor related, locus 1|homeobox protein NK-6 homolog A|homeobox protein Nkx-6.1
Swissprots P78426
Accessions AAD11962 EAX05949 P78426 BC160030 AAI60030 XM_006714230 XP_006714293 NM_006168 NP_006159
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Pancreatic beta cells.
Top Pathways Maturity onset diabetes of the young

Human Nkx6-1 ORF clone(NM_006168.2) - CDCH391947 from Creative Biomart

Species Human
Accession NM_006168.2

Human Nkx6-1 ORF clone(NM_006168.2) - CDCH391947 from Creative biogene

Species Human

Human NKX6 cDNA Clone(NM_006168.2) - CDFH012585 from Creative biogene

Species Human
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