NKX6-1

Gene Symbol NKX6-1
Entrez Gene 4825
Alt Symbol NKX6.1, NKX6A
Species Human
Gene Type protein-coding
Description NK6 homeobox 1
Other Description NK homeo box, family 6, member A|NK homeobox, family 6, A|NK6 transcription factor homolog A|NK6 transcription factor related, locus 1|homeobox protein NK-6 homolog A|homeobox protein Nkx-6.1
Swissprots P78426
Accessions AAD11962 EAX05949 P78426 BC160030 AAI60030 XM_006714230 XP_006714293 NM_006168 NP_006159
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Pancreatic beta cells.
Top Pathways Maturity onset diabetes of the young

Nkx-6.1 CRISPR/Cas9 KO Plasmid (h) - sc-401997 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 HDR Plasmid (h) - sc-401997-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 Double Nickase Plasmid (h) - sc-401997-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 Double Nickase Plasmid (h2) - sc-401997-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 CRISPR Activation Plasmid (h) - sc-401997-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 CRISPR Activation Plasmid (h2) - sc-401997-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 Lentiviral Activation Particles (h) - sc-401997-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 Lentiviral Activation Particles (h2) - sc-401997-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 siRNA (h) - sc-38731 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nkx-6.1 shRNA Plasmid (h) - sc-38731-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nkx-6.1 shRNA (h) Lentiviral Particles - sc-38731-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NKX6.1 RNAi - H00004825-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU152421 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15338 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15338 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NKX6-1 siRNA (Human) - CRH3203 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Nkx-6.1 HDR Plasmid (h2) - sc-401997-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-6.1 CRISPR/Cas9 KO Plasmid (h2) - sc-401997-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human NKX6-1(NM_006168.2) - SHR012270 from Creative biogene

Category siRNA
Species Reactivities Human

Human NKX6-1 siRNA - orb263705 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NKX6-1 shRNA Plasmid (Human) - CHH3203 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NKX6-1 miRNA 3'UTR clone - MiUTR1H-06780 from Creative biogene

Species Reactivities Human
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