MAN1B1

Gene Symbol	MAN1B1
Entrez Gene	11253
Alt Symbol	ERMAN1, MANA-ER, MRT15
Species	Human
Gene Type	protein-coding
Description	mannosidase, alpha, class 1B, member 1
Other Description	ER alpha 1,2-mannosidase|Man9GlcNAc2-specific processing alpha-mannosidase|endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase|endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1
Swissprots	Q9Y5K7 Q9BRS9 Q5VSG3 Q9UKM7
Accessions	EAW88345 EAW88346 EAW88347 Q9UKM7 AB209276 BAD92513 AF145732 AAD45504 AF148509 AAF03215 AI312031 AK074559 BAC11060 AK074699 BAG51987 AK094878 AK126926 AK127005 AK128033 AK128257 BAG54653 AK128341 BAG54664 AK130143 AK298480 BAG60691 AK299043 BAG61117 AK309808 AK315797 AL110221 CAB53680 AY358465 AAQ88830 BC002953 AAH02953 BC006079 AAH06079 BE731944 BM848429 BQ448144 CR749534 CAH18340 DA763005 DQ891861 ABM82787 DQ895050 ABM85976 XM_006716945 XP_006717008 NM_016219 NP_057303 NR_045720 NR_045721
Function	Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2). {ECO:0000269|PubMed:12090241, ECO:0000269|PubMed:18003979}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10409699}; Single-pass type II membrane protein {ECO:0000269|PubMed:10409699}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:10409699, ECO:0000269|PubMed:10521544}.
Top Pathways	N-Glycan biosynthesis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAN1B1 protein fragment - ab161379 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human ERManI Protein - H00011253-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human MAN1B1 protein - orb180256 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

MAN1B1 - H00011253-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAN1B1 - H00011253-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAN1B1 fusion protein - ag7455 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MAN1B1, His-tagged - MAN1B1-135H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-manno - CSB-YP891727HU CSB-EP891727HU CSB-BP891727HU CSB-MP891727HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MAN1B1 - TP720726 from Acris Antibodies Category Protein Prices $139.00 Sizes 10 µg Source HEK293 cells Species Human

ERManI Recombinant Protein Antigen - NBP2-14216PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MAN1B1 Peptide, Human - M34GP09134H from Creative Peptides Category Peptide Source Synthetic. Species Human

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (MAN1B1), Recombinant Protein - MBS1300352 from MyBioSource Category Protein Prices $815.00, $815.00, $1,040.00, $1,040.00, $1,155.00, $1,155.00, $1,610.00, $1,610.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MAN1B1, Recombinant Protein - MBS8249425 from MyBioSource Category Protein Prices $205.00, $465.00, $2,080.00 Sizes 10 µg, 50 µg, 500 µg Source Human cells Species Human

Recombinant Human ER α-1,2-Mannosidase,MAN1B1 (C-6His) - AP75404 from Signalway Antibody Category Protein Prices $279.00, $579.00, $2,289.00, $3,209.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source Human Cells Species Human

ER Alpha-1,2-Mannosidase Recombinant Protein - 91-681 from ProSci Category Protein Prices $425.00 Sizes 50 µg Source Human Cells Species Human

Human MAN1B1 protein - orb392115 from Biorbyt Category Protein Species Human

Search more