BRAF

Gene Symbol	BRAF
Entrez Gene	673
Alt Symbol	B-RAF1, BRAF1, NS7, RAFB1
Species	Human
Gene Type	protein-coding
Description	B-Raf proto-oncogene, serine/threonine kinase
Other Description	94 kDa B-raf protein|B-Raf proto-oncogene serine/threonine-protein kinase (p94)|murine sarcoma viral (v-raf) oncogene homolog B1|proto-oncogene B-Raf|serine/threonine-protein kinase B-raf|v-raf murine sarcoma viral oncogene homolog B|v-raf murine sarcoma viral oncogene homolog B1
Swissprots	P15056 Q9UDP8 Q13878 Q9Y6T3 Q3MIN6 A4D1T4
Accessions	AAD15551 AAD43193 AAS00359 ACD11489 ADQ00186 ADX94397 AIE38317 CAA46301 CAZ68014 CBK51920 EAL24023 EAW83964 EAW83965 P15056 AA252358 AA834931 AI203435 AK054801 AK094023 AK098095 AK124257 AK314346 AW971583 BC038966 BC101757 AAI01758 BC112079 AAI12080 BM263585 DB454480 DN996440 HM437233 ADN43065 M21001 AAA96495 M95712 AAA35609 XM_005250045 XP_005250102 XM_005250046 XP_005250103 XM_011516529 XP_011514831 XM_011516530 XP_011514832 XR_242190 XR_927520 XR_927521 XR_927522 XR_927523 NM_004333 NP_004324
Function	Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway. {ECO:0000269|PubMed:21441910}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm. Cell membrane {ECO:0000250}. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. {ECO:0000250}.
Tissue Specificity	Brain and testis.
Top Pathways	Chemokine signaling pathway, Vascular smooth muscle contraction, Hepatitis C, Neurotrophin signaling pathway, Alcoholism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat Phospho-BRAF / B-Raf (Ser602) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1293 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat Phospho-BRAF / B-Raf (Thr753) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1724 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat BRAF / B-Raf ELISA Kit (Cell-Based ELISA) - LS-F1832 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human Phospho-BRAF / B-Raf (Ser446) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1676 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Human BRAF / B-Raf ELISA Kit (Sandwich ELISA) - LS-F9008 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Human BRAF ELISA Kit - abx150833 from Abbexa Category ELISA Kit Sensitivity 0.124 ng/ml Range 0.313 ng/ml - 20 ng/ml

B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF), Human, ELISA Kit - SEG347Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.124ng/mL Range 0.312-20ng/mL

Serine/threonine-protein kinase B-raf (BRAF), Human, ELISA Kit - CSB-EL002791HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Serine/threonine-protein kinase B-raf (BRAF), Human, ELISA Kit - E01S0332 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

PNA BRAF Mutation Detection Kit - KA2102 from Acris Antibodies Category ELISA Kit Prices $2,230.00 Sizes 1 kit

Anserine PIV IgD ELISA Kit - AP0012 from NeoScientific Category ELISA Kit Prices $300.00, $480.00 Sizes 100 µl, 200 µl

B-RAF Colorimetric Cell-Based ELISA Kit - CB5078 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

B-RAF (Phospho-Ser602) Colorimetric Cell-Based ELISA Kit - CBP1297 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

B-RAF (Phospho-Ser446) Colorimetric Cell-Based ELISA Kit - CBP1739 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

B-Raf (Phospho-Thr753) Colorimetric Cell-Based ELISA Kit - CBP1809 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human BRAF(B-Raf Proto Oncogene Serine/Threonine Protein Kinase) ELISA Kit - E-EL-H1614 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

BRAF, ELISA Kit - MBS2516341 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Serine/threonine protein kinase B raf (BRAF), ELISA Kit - MBS7205603 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

v-raf murine sarcoma viral oncogene homolog B1, ELISA Kit - MBS912465 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human BRAF is typically less than 7.81 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml -2000 pg/ml.

ELISA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) - SEG347Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

B-Raf Kinase Assay Kit, Chemiluminescence Detection - 17-359 from EMD Millipore Category Assay Kit

Human Serine/threonine-protein kinase B-raf(BRAF) ELISA kit - CSB-EL002791HU from Cusabio Category ELISA Kit Sensitivity 7.8pg/ml Range 31.25 pg/ml-2000 pg/ml

ELISA Kit for B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) - SEG347Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human BRAF / B-Raf ELISA Kit (Sandwich ELISA) - LS-F22093 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.188 ng/ml Range 0.313-20 ng/ml

B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF), Human, ELISA Kit - DL-BRAF-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

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