BRAF

Gene Symbol BRAF
Entrez Gene 673
Alt Symbol B-RAF1, BRAF1, NS7, RAFB1
Species Human
Gene Type protein-coding
Description B-Raf proto-oncogene, serine/threonine kinase
Other Description 94 kDa B-raf protein|B-Raf proto-oncogene serine/threonine-protein kinase (p94)|murine sarcoma viral (v-raf) oncogene homolog B1|proto-oncogene B-Raf|serine/threonine-protein kinase B-raf|v-raf murine sarcoma viral oncogene homolog B|v-raf murine sarcoma viral oncogene homolog B1
Swissprots P15056 Q9UDP8 Q13878 Q9Y6T3 Q3MIN6 A4D1T4
Accessions AAD15551 AAD43193 AAS00359 ACD11489 ADQ00186 ADX94397 AIE38317 CAA46301 CAZ68014 CBK51920 EAL24023 EAW83964 EAW83965 P15056 AA252358 AA834931 AI203435 AK054801 AK094023 AK098095 AK124257 AK314346 AW971583 BC038966 BC101757 AAI01758 BC112079 AAI12080 BM263585 DB454480 DN996440 HM437233 ADN43065 M21001 AAA96495 M95712 AAA35609 XM_005250045 XP_005250102 XM_005250046 XP_005250103 XM_011516529 XP_011514831 XM_011516530 XP_011514832 XR_242190 XR_927520 XR_927521 XR_927522 XR_927523 NM_004333 NP_004324
Function Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway. {ECO:0000269|PubMed:21441910}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm. Cell membrane {ECO:0000250}. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. {ECO:0000250}.
Tissue Specificity Brain and testis.
Top Pathways Chemokine signaling pathway, Vascular smooth muscle contraction, Hepatitis C, Neurotrophin signaling pathway, Alcoholism

BRAF overexpression lysate - LY401382 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

BRAF 293 Cell Lysate - 401261 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Species Mouse
Disease Cancer

B-Raf Overexpression Lysate (Native) - NBL1-08021 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

BRAF Over-expression Lysate Product - GWB-A190AD from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human BRAF Knockdown Stable Cell Line - CSC-DC001519 from Creative biogene

Category Cell Line
Species Human

Human BRAF Knockout Cell Line-HeLa - CSC-RT1742 from Creative biogene

Category Cell Line
Species Human

BRAF KO Cell Lysate-HeLa - CLKO-1589 from Creative biogene

Category Cell Lysate
Search more