BRAF

Gene Symbol	BRAF
Entrez Gene	673
Alt Symbol	B-RAF1, BRAF1, NS7, RAFB1
Species	Human
Gene Type	protein-coding
Description	B-Raf proto-oncogene, serine/threonine kinase
Other Description	94 kDa B-raf protein|B-Raf proto-oncogene serine/threonine-protein kinase (p94)|murine sarcoma viral (v-raf) oncogene homolog B1|proto-oncogene B-Raf|serine/threonine-protein kinase B-raf|v-raf murine sarcoma viral oncogene homolog B|v-raf murine sarcoma viral oncogene homolog B1
Swissprots	P15056 Q9UDP8 Q13878 Q9Y6T3 Q3MIN6 A4D1T4
Accessions	AAD15551 AAD43193 AAS00359 ACD11489 ADQ00186 ADX94397 AIE38317 CAA46301 CAZ68014 CBK51920 EAL24023 EAW83964 EAW83965 P15056 AA252358 AA834931 AI203435 AK054801 AK094023 AK098095 AK124257 AK314346 AW971583 BC038966 BC101757 AAI01758 BC112079 AAI12080 BM263585 DB454480 DN996440 HM437233 ADN43065 M21001 AAA96495 M95712 AAA35609 XM_005250045 XP_005250102 XM_005250046 XP_005250103 XM_011516529 XP_011514831 XM_011516530 XP_011514832 XR_242190 XR_927520 XR_927521 XR_927522 XR_927523 NM_004333 NP_004324
Function	Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway. {ECO:0000269|PubMed:21441910}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm. Cell membrane {ECO:0000250}. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. {ECO:0000250}.
Tissue Specificity	Brain and testis.
Top Pathways	Chemokine signaling pathway, Vascular smooth muscle contraction, Hepatitis C, Neurotrophin signaling pathway, Alcoholism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human B Raf (mutated K601 E) protein fragment - ab201428 from Abcam Category Protein Prices $294.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active human B Raf (mutated V599) protein fragment - ab84554 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Active human B Raf (mutated V600 E) protein fragment - ab196061 from Abcam Category Protein Prices $593.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human B Raf/p50 recombinant protein fragment - ab42596 from Abcam Category Protein Prices $321.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human B Raf protein fragment - ab196139 from Abcam Category Protein Prices $612.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human B Raf protein fragment - ab55690 from Abcam Category Protein Prices $294.00, $1,845.00 Sizes 10 µg, 100 µg Source Baculovirus infected sf9 cells Species Human

Active human B Raf protein fragment(T599_V600insT) - ab201412 from Abcam Category Protein Prices $294.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Human B Raf peptide - ab40898 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human B Raf protein fragment - ab152242 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BRAF / B-Raf Antibody Blocking Peptide - LS-E30938 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E7338 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E7406 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Blocking Peptide - LS-E7359 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E7366 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E7372 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E31446 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E9282 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E9283 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E9284 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAF / B-Raf Antibody Blocking Peptide - LS-E9281 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

B-Raf Partial Recombinant Protein - H00000673-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

B-Raf Recombinant Protein - P4833 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

B-Raf Recombinant Protein - P4636 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

B-Raf Peptide - NBP1-76269PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

B-Raf Peptide - P1646 from Novus Biologicals Category Peptide Species Human

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