Lrpprc

Gene Symbol Lrpprc
Entrez Gene 72416
Alt Symbol 3110001K13Rik, C76645, Gp130, Lrp130, Lsfc
Species Mouse
Gene Type protein-coding
Description leucine-rich PPR-motif containing
Other Description 130 kDa leucine-rich protein|leucine rich protein LRP130|leucine-rich PPR motif-containing protein, mitochondrial
Swissprots Q9CRX4 Q8K4V0 Q6PB66
Accessions EDL38586 Q6PB66 AK013955 BAB29082 AK039751 AK138527 AK149503 BC004681 AAH04681 BC059862 AAH59862 BC060199 S81177 XM_011246643 XP_011244945 NM_028233 NP_082509
Function May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters (By similarity). Binds single-stranded DNA. {ECO:0000250}.
Subcellular Location Mitochondrion {ECO:0000250}. Nucleus {ECO:0000269|PubMed:12071956}. Nucleus, nucleoplasm {ECO:0000250}. Nucleus inner membrane {ECO:0000250}. Nucleus outer membrane {ECO:0000250}.
Tissue Specificity Strongly expressed in heart, liver and kidney. Weakly expressed in brain, skeletal muscle and testes. {ECO:0000269|PubMed:12071956}.

LRP130 (E-12) - sc-376657 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LRP130 (E-12): sc-376657. Western blot analysis of LRP130 expression in NIH/3T3 whole cell lysate.

gp130/CD130 Antibody (125623) [Unconjugated] - MAB4681 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 125623
Mouse splenocytes were stained with Rat Anti-Mouse CD3 PE‑conjugated Monoclonal Antibody (Catalog # FAB4841P) and either (A) Rat Anti-Mouse gp130 Monoclonal Antibody (Catalog # MAB4681) or (B) Rat IgG2A Isotype Control (Catalog # MAB006) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins.

gp130/CD130 Antibody [Unconjugated] - AF468 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Recombinant Human IL‑6 (Catalog # 206-IL) inhibits proliferation in the the M1 mouse myeloid leukemia cell line in a dose-dependent manner (orange line). Activity elicited by Recombinant Human IL‑6 (20 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse gp130 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF468). The ND50 is typically 0.3-1.0 µg/mL.

gp130/CD130 Antibody (KGP130) - NBP2-00335 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone KGP130
Flow Cytometry: CD130 Antibody (KGP130) [NBP2-00335] - Staining of BALB/c splenocytes with Anti-Mouse CD3e FITC and 0.125 ug of Rat IgG2a kappa Isotype Control Purified (left) or 0.125 ug of Anti-Mouse CD130 Purified (right) followed by F(ab')2 Anti-Rat IgG PE . Cells in the lymphocyte gate were used for analysis.

gp130/CD130 Antibody (125623) [Allophycocyanin] - FAB4681A-100 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 125623

gp130/CD130 Antibody (125623) [Biotin] - BAM4681 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 125623

gp130/CD130 Antibody [Biotin] - BAF468 from Novus Biologicals

Prices $420.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

gp130/CD130 Antibody (125623) [Allophycocyanin] - FAB4681A-025 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 125623

gp130/CD130 Antibody (125623) [PE] - FAB4681P-100 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 125623

gp130/CD130 Antibody (125623) [PE] - FAB4681P-025 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 125623

gp130/CD130 Antibody (KGP130) [Alexa Fluor (R) 405] - NBP2-00335AF405 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [PerCP] - NBP2-00335PCP from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [DyLight 350] - NBP2-00335UV from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [DyLight 405] - NBP2-00335V from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [PE] - NBP2-00335PE from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [7C] - NBP2-00335V2 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [Alexa Fluor (R) 700] - NBP2-00335AF700 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [Alexa Fluor (R) 647] - NBP2-00335AF647 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [Alexa Fluor (R) 488] - NBP2-00335AF488 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [DyLight 488] - NBP2-00335G from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [DyLight 405LS] - NBP2-00335V3 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [DyLight 755] - NBP2-00335IR from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [Allophycocyanin] - NBP2-00335APC from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

gp130/CD130 Antibody (KGP130) [DyLight 680] - NBP2-00335FR from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone KGP130

CD130 antibody [15D27] - GTX53428 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rat
Clonality Monoclonal
Clone 15D27
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