Lrpprc

Gene Symbol	Lrpprc
Entrez Gene	72416
Alt Symbol	3110001K13Rik, C76645, Gp130, Lrp130, Lsfc
Species	Mouse
Gene Type	protein-coding
Description	leucine-rich PPR-motif containing
Other Description	130 kDa leucine-rich protein|leucine rich protein LRP130|leucine-rich PPR motif-containing protein, mitochondrial
Swissprots	Q9CRX4 Q8K4V0 Q6PB66
Accessions	EDL38586 Q6PB66 AK013955 BAB29082 AK039751 AK138527 AK149503 BC004681 AAH04681 BC059862 AAH59862 BC060199 S81177 XM_011246643 XP_011244945 NM_028233 NP_082509
Function	May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters (By similarity). Binds single-stranded DNA. {ECO:0000250}.
Subcellular Location	Mitochondrion {ECO:0000250}. Nucleus {ECO:0000269|PubMed:12071956}. Nucleus, nucleoplasm {ECO:0000250}. Nucleus inner membrane {ECO:0000250}. Nucleus outer membrane {ECO:0000250}.
Tissue Specificity	Strongly expressed in heart, liver and kidney. Weakly expressed in brain, skeletal muscle and testes. {ECO:0000269|PubMed:12071956}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Gp130/IL6ST, Mouse, ELISA Kit - PB-0577 from ARP American Research Products Category ELISA Kit Prices $418.00 Sizes 96 t Sensitivity < 10 pg/ml Range 125pg/ml-8000pg/ml

Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC), Mouse, ELISA Kit - CSB-EL013105MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mouse gp130 ELISA Kit - MG0223 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Gp130/IL6ST ELISA Kit - DEIA10965 from Creative Diagnostics Category ELISA Kit Range 125pg/mL-8000pg/mL

Mouse gp130(Glucoprotein 130) ELISA Kit - E-EL-M0560 from Elabscience Category ELISA Kit Sensitivity 75.00 pg/mL Range 125.00—8000 pg/mL

Mouse gp130 (Glucoprotein 130) CLIA Kit - E-CL-M0338 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

leucine-rich PPR-motif containing, ELISA Kit - MBS906147 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse LRPPRC is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml-1600 pg/ml.

Mouse Leucine-rich PPR motif-containing protein, mitochondrial(LRPPRC) ELISA kit - CSB-EL013105MO from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml. Range 25 pg/ml-1600 pg/ml

Mouse Glucoprotein 130 ELISA - E03G0216 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

Mouse gp130 (Glucoprotein 130) CLIA Kit - E-CL-M0338 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 75pg/mL Range 125-8000pg/mL

Glucoprotein 130 (gp130), Mouse, ELISA Kit - DL-gp130-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 4.69-300 ng/mL

Mouse Gp130/IL6ST ELISA Kit - EA100398 from Acris Antibodies Category ELISA Kit Prices $389.00 Sizes 1 kit Range 10

Mouse gp130 ELISA kit - orb79229 from Biorbyt Category ELISA Kit Prices $765.00, $1,292.00, $2,754.00 Sizes 96 well, 192 assays, 480 assays

Mouse gp130 ELISA Kit - abx574324 from Abbexa Category ELISA Kit Sensitivity 48 pg/ml Range 125 pg/ml - 8000 pg/ml

Gp130/IL6ST - EKM180 from Nordic BioSite Sensitivity 0.075ng/ml Range 0.125-8ng/ml

Gp130/IL6ST - EKM0180 from Nordic BioSite Sensitivity 0.075ng/ml Range 0.125-8ng/ml

Custom Mouse gp130 Speed ELISA Kit - orb384925 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

Mouse gP130 ELISA Kit - EKB02160 from Biomatik Category ELISA Kit Prices $527.00, $2,503.00, $4,848.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 30pg/ml Range 41-10000pg/ml

Mouse Gp130/IL6ST ELISA Kit - E054232 from Biobool Category ELISA Kit Sensitivity < 75pg/ml

Mouse gp130 ELISA Kit - E054236 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of mouse gp130 is typically less than 48pg/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding

Mouse gp130/CD130 ELISA Kit - E054237 from Biobool Category ELISA Kit

Mouse Lrpprc ELISA Kit - E058581 from Biobool Category ELISA Kit

Mouse gp130 ELISA Kit - EMG0223 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

LRPPRC ELISA Kit (Mouse) (OKCA01706) - OKCA01706 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 6.25 pg/mL Range 25 - 1,600 pg/mL

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