GAPDH

Gene Symbol GAPDH
Entrez Gene 100009074
Alt Symbol -
Species Rabbit
Gene Type protein-coding
Description glyceraldehyde-3-phosphate dehydrogenase
Other Description peptidyl-cysteine S-nitrosylase GAPDH
Swissprots P46406 Q4AC92
Accessions P46406 AB128158 BAD04921 AB231852 BAE19661 DQ403051 ABD77184 L23961 AAA85218 V00884 CAA24253 NM_001082253 NP_001075722
Function Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in infl
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. {ECO:0000250}.
Top Pathways Glycolysis / Gluconeogenesis, Alzheimer's disease, Biosynthesis of amino acids, Carbon metabolism

GAPDH Antibody (71.1) [HRP] - NB110-40405 from Novus Biologicals

Prices $219.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 71.1
Western Blot: GAPDH Antibody (71.1) [HRP] [NB110-40405] - Total cell extract of A431 cells was separated on SDS-PAGE and blotted with Monoclonal Anti-GAPDH, Peroxidase conjugate . The antibody was developed with chemiluminescent substrate. Lanes: 1. 1:20,000 antibody 2. 1:40,000 antibody 3. 1:60,000 antibody 4. 1:80,000 antibody

GAPDH Antibody (OASA02828) - OASA02828 from Aviva Systems Biology

Prices $355.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 4G5

GAPDH Antibody (OASA03787) - OASA03787 from Aviva Systems Biology

Prices $355.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 6C5

GAPDH Antibody - Biotin Conjugated (OASA11367) - OASA11367 from Aviva Systems Biology

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6C5

GAPDH Antibody - DyLight 680 Conjugated (OASA11368) - OASA11368 from Aviva Systems Biology

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6C5

GAPDH Antibody - DyLight 800 Conjugated (OASA11369) - OASA11369 from Aviva Systems Biology

Prices $420.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6C5

GAPDH Antibody - HRP Conjugated (OASA11370) - OASA11370 from Aviva Systems Biology

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6C5

GAPDH antibody (HRP) - GTX40599 from GeneTex

Prices $199.00
Sizes 1 mg
Host Goat
Clonality Polyclonal

Anti -GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) - 214849 from USBiological Life Science

Host Mouse
Clonality Monoclonal

Anti -GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) (HRP) - 214850 from USBiological Life Science

Host Mouse
Clonality Monoclonal

Anti -Glyceraldehyde-3-phosphate Dehydrogenase - 169050 from USBiological Life Science

Host Sheep
Clonality Polyclonal

Anti -Glyceraldehyde-3-phosphate Dehydrogenase - 169051 from USBiological Life Science

Host Sheep
Clonality Polyclonal

Anti -Glyceraldehyde-3-phosphate Dehydrogenase (Biotin) - 169054 from USBiological Life Science

Host Sheep
Clonality Polyclonal

Anti -Glyceraldehyde-3-phosphate Dehydrogenase (GAPD, GAPDH) - G8140-13B from USBiological Life Science

Host Sheep
Clonality Polyclonal

Anti -Glyceraldehyde-3-phosphate Dehydrogenase (GAPD, GAPDH) - G8140-13C from USBiological Life Science

Host Sheep
Clonality Polyclonal

Anti -Glyceraldehyde-3-phosphate Dehydrogenase (GAPD, GAPDH) (Biotin) - G8140-13D from USBiological Life Science

Host Sheep
Clonality Polyclonal

Anti-Glyceraldehyde-3-phosphate dehydrogenase - 21-1724 from ARP American Research Products

Prices $399.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-Glyceraldehyde-3-phosphate dehydrogenase - 21-1725 from ARP American Research Products

Prices $499.00
Sizes 200 µl
Host Sheep
Clonality Polyclonal

Anti-Glyceraldehyde-3-phosphate dehydrogenase - 21-1726 from ARP American Research Products

Prices $499.00
Sizes 200 µg
Host Sheep
Clonality Polyclonal

Glyceraldehyde-3-phosphate dehydrogenase, Polyclonal Antibody - MBS573479 from MyBioSource

Prices $280.00
Sizes 10 mg
Host Sheep
Clonality Polyclonal

Rabbit GAPDH Antibody (DyLight®680) - GWB-Q01255 from Genway Biotech

Prices $474.00
Sizes 100 µg
Host Mouse
Clone 6C5

Rabbit GAPDH Antibody (DyLight®680) - GWB-Q01256 from Genway Biotech

Prices $451.00
Sizes 100 µg
Host Mouse
Clone 6C5
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