GAPDH

Gene Symbol GAPDH
Entrez Gene 100009074
Alt Symbol -
Species Rabbit
Gene Type protein-coding
Description glyceraldehyde-3-phosphate dehydrogenase
Other Description peptidyl-cysteine S-nitrosylase GAPDH
Swissprots P46406 Q4AC92
Accessions P46406 AB128158 BAD04921 AB231852 BAE19661 DQ403051 ABD77184 L23961 AAA85218 V00884 CAA24253 NM_001082253 NP_001075722
Function Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in infl
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. {ECO:0000250}.
Top Pathways Glycolysis / Gluconeogenesis, Alzheimer's disease, Biosynthesis of amino acids, Carbon metabolism

Rabbit GAPDH protein - orb79665 from Biorbyt

Category Protein
Prices $561.00, $918.00, $1,275.00
Sizes 100 µg, 500 µg, 1 mg
Species Rabbit

GAPDH protein (Rabbit) - 30R-AG005 from Fitzgerald

Category Protein
Prices $346.50
Sizes 100 µg
Species Rabbit

Native Rabbit GAPDH - GAPDH-126R from Creative Biomart

Category Protein
Source Rabbit
Species Rabbit

Recombinant Rabbit Glyceraldehyde-3-phosphate dehydrogenase(GAPDH) - CSB-YP009232RB CSB-EP009232RB CSB-BP009232RB CSB-MP009232RB from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Rabbit

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), Recombinant Protein - MBS947994 from MyBioSource

Category Protein
Prices $1,095.00, $1,095.00, $1,325.00, $1,325.00, $1,725.00, $1,725.00, $2,185.00, $2,185.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Rabbit
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