| Gene Symbol |
NPHS2
|
| Entrez Gene |
7827
|
| Alt Symbol |
PDCN, SRN1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nephrosis 2, idiopathic, steroid-resistant (podocin)
|
| Other Description |
podocin
|
| Swissprots |
Q8N6Q5 B1AM32 B1AM33 Q9NP85
|
| Accessions |
CAB83272 EAW91049 EAW91050 Q9NP85 AJ279254 CAB83216 BC029141 AAH29141 BI831348 BX095913 XM_005245483 XP_005245540 XM_006711529 XP_006711592 NM_001297575 NP_001284504 NM_014625 NP_055440
|
| Function |
Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
|
| Subcellular Location |
Isoform 1: Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli.
|