Gene Symbol | NPHS2 |
---|---|
Entrez Gene | 7827 |
Alt Symbol | PDCN, SRN1 |
Species | Human |
Gene Type | protein-coding |
Description | nephrosis 2, idiopathic, steroid-resistant (podocin) |
Other Description | podocin |
Swissprots | Q8N6Q5 B1AM32 B1AM33 Q9NP85 |
Accessions | CAB83272 EAW91049 EAW91050 Q9NP85 AJ279254 CAB83216 BC029141 AAH29141 BI831348 BX095913 XM_005245483 XP_005245540 XM_006711529 XP_006711592 NM_001297575 NP_001284504 NM_014625 NP_055440 |
Function | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. |
Subcellular Location | Isoform 1: Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. |
Tissue Specificity | Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli. |
Podocin CRISPR/Cas9 KO Plasmid (h) - sc-400930 from Santa Cruz Biotechnology
|
||||||||
Podocin HDR Plasmid (h) - sc-400930-HDR from Santa Cruz Biotechnology
|
||||||||
Podocin Double Nickase Plasmid (h) - sc-400930-NIC from Santa Cruz Biotechnology
|
||||||||
Podocin Double Nickase Plasmid (h2) - sc-400930-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Podocin CRISPR Activation Plasmid (h) - sc-400930-ACT from Santa Cruz Biotechnology
|
||||||||
Podocin CRISPR Activation Plasmid (h2) - sc-400930-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Podocin Lentiviral Activation Particles (h) - sc-400930-LAC from Santa Cruz Biotechnology
|
||||||||
Podocin Lentiviral Activation Particles (h2) - sc-400930-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Podocin siRNA (h) - sc-40859 from Santa Cruz Biotechnology
|
||||||||
Podocin shRNA Plasmid (h) - sc-40859-SH from Santa Cruz Biotechnology
|
||||||||
Podocin shRNA (h) Lentiviral Particles - sc-40859-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU085591 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15455 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15455 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR05033 from Sigma-Aldrich
|
||||||||
NPHS2 siRNA (Human) - CRH5286 from Cohesion Biosciences
|
||||||||
Podocin CRISPR/Cas9 KO Plasmid (h2) - sc-400930-KO-2 from Santa Cruz Biotechnology
|
||||||||
Podocin HDR Plasmid (h2) - sc-400930-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human NPHS2 (NM_014625.2) - SHH354260 from Creative biogene
|
||||||||
Human NPHS2 siRNA - orb265788 from Biorbyt
|
||||||||
NPHS2 shRNA Plasmid (Human) - CHH5286 from Cohesion Biosciences
|
||||||||
NPHS2 miRNA 3'UTR clone - MiUTR3H-07075 from Creative biogene
|