Pdgfrb

Gene Symbol	Pdgfrb
Entrez Gene	24629
Alt Symbol	PDGFR-1
Species	Rat
Gene Type	protein-coding
Description	platelet derived growth factor receptor, beta polypeptide
Other Description	CD140 antigen-like family member B|PDGF-R-beta|PDGFR-beta|Platelet-derived growth factor receptor, beta|beta platelet-derived growth factor receptor|beta-type platelet-derived growth factor receptor|platelet-derived growth factor receptor 1|platelet-derived growth factor receptor beta|platelet-derived growth factor receptor beta variant 1
Swissprots	Q925F7 Q05030 Q8R406
Accessions	EDM14586 Q05030 AF359356 AAK43716 AY090783 AAM09098 DQ979389 ABJ53143 Z14119 CAA78489 XM_006254789 XP_006254851 XM_008772084 XP_008770306 NM_031525 NP_113713
Function	Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli. Promotes rearrangement of the actin cytoskeleton and the formation of membrane ruffles. Binding of its cognate ligands - homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGF
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Lysosome lumen {ECO:0000250}. Note=After ligand binding, the autophosphorylated receptor is ubiquitinated and internalized, leading to its degradation. {ECO:0000250}.
Top Pathways	Rap1 signaling pathway, MicroRNAs in cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Beta-type platelet-derived growth factor receptor (PDGFRB), Rat, ELISA Kit - CSB-EL017713RA from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Beta-type platelet-derived growth factor receptor (PDGFRB), Rat, ELISA Kit - E02B0960 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Beta-type platelet-derived growth factor receptor, Pdgfrb, Rat, ELISA Kit - E2061r from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS264040 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS267400 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity the minimum detectable Chicken p-ERK up to 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS268180 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS263848 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS267200 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS262088 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Up to 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS2602485 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Platelet Derived Growth Factor Receptor Beta (PDGFRb), ELISA Kit - MBS2023313 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PDGFRb is typically less than 0.063ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Rat Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit - CSB-EL017713RA from Cusabio Category ELISA Kit Sensitivity 11.75pg/ml Range 47 pg/ml-3000 pg/ml

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS260647 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rat Beta-type platelet-derived growth factor receptor ELISA Kit - abx256601 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Rat Platelet-Derived Growth Factor Receptor beta ELISA Kit - abx055233 from Abbexa Category ELISA Kit

platelet-derived growth factor receptor, beta polypeptide, ELISA Kit - MBS928462 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat PDGFRB is typically less than 11.75 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 47 pg/ml -3000 pg/ml.

PDGFRbeta (Platelet Derived Growth Factor Receptor Beta), CLIA Kit - MBS2532400 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) - SEC061Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.062ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Rat Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA Kit - EKC38745 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity 11.75 pg/ml Range 47 pg/ml-3000 pg/ml

Rat Beta-type platelet-derived growth factor receptor ELISA Kit - EKE53401 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 0.312-20 ng/mL

PDGFRb - EKR1252 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Rat Pdgfrb ELISA Kit - E093366 from Biobool Category ELISA Kit

PDGFRB ELISA Kit (Rat) (OKEH03443) - OKEH03443 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity 0.156 ng/mL Range 0.312 - 20 ng/mL

Rat Beta-type platelet-derived growth factor receptor ELISA Kit - EK4235 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 0.312-20 ng/ml

phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit - MBS2609649 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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