C8A

Gene Symbol C8A
Entrez Gene 731
Alt Symbol -
Species Human
Gene Type protein-coding
Description complement component 8, alpha polypeptide
Other Description complement component 8 subunit alpha|complement component C8 alpha chain
Swissprots Q13668 A2RUI4 P07357 A2RUI5 Q9H130
Accessions AAA82124 EAX06644 EAX06645 EAX06646 P07357 AK309596 BC020702 AAH20702 BC132911 AAI32912 BC132913 AAI32914 HQ258328 ADR83082 M16974 AAA52200 XM_011542079 XP_011540381 NM_000562 NP_000553
Function Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. {ECO:0000269|PubMed:17872444, ECO:0000269|PubMed:7440581}.
Subcellular Location Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein. Inserts into the cell membrane of target cells.
Top Pathways Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis

C8α (S-16) - sc-323687 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

C8α (T-18) - sc-323686 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
C8α (T-18): sc-323686. Western blot analysis of C8α expression in non-transfected: sc-117752 (A) and human C8α transfected: sc-372979 (B) 293T whole cell lysates.

Anti-C8 antibody [056B-373] - ab59140 from Abcam

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 056B-373

Anti-C8A (56-70) antibody produced in rabbit - SAB1104759 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C8A was separated on SDS-PAGE, blotted with Anti-C8A (56-70) (<B>Cat. No. SAB1104759</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

C8A antibody - 25289-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 25289-1-AP( C8A Antibody) at dilution of 1:700

C8A antibody - H00000731-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

C8A antibody - 25289-1-AP from Proteintech Group

Prices $279.00
Sizes con: 43 μg/150μl
Host Rabbit
Clonality Polyclonal
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 25289-1-AP( C8A Antibody) at dilution of 1:700

Anti-C8A monoclonal antibody, clone 167C-484 - DCABH-9256 from Creative Diagnostics

Host Mouse
Clonality Monoclonal
Clone 167C-484

Human Complement C8 Antibody - 15351-05011 from AssayPro

Prices $145.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal
Clone None

Human Complement C8 Antibody (Biotin Conjugate) - 15351-05021 from AssayPro

Prices $175.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal
Clone None

C8A - A9688 from NeoScientific

Prices $480.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

C8A Polyclonal Antibody - A9688 from ABclonal

Prices $200.00, $480.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

C8A Antibody - abx123942 from Abbexa

Host Rabbit
Clonality Polyclonal

Human Complement C8 Antibody (FITC Conjugate) - 15351-05041 from AssayPro

Prices $265.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal
Clone None

Human Complement C8 Antibody (RPE Conjugate) - 15351-05051 from AssayPro

Prices $350.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal
Clone None

Human Complement C8 Antibody (APC Conjugate) - 15351-05061 from AssayPro

Prices $350.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal
Clone None

Human Complement C8 Antibody (PerCP Conjugate) - 15351-05071 from AssayPro

Prices $390.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal
Clone None

C8A, Polyclonal Antibody - MBS767371 from MyBioSource

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

C8A, Polyclonal Antibody - MBS9129648 from MyBioSource

Prices $285.00, $555.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

C8A, Polyclonal Antibody - MBS7044857 from MyBioSource

Prices $120.00, $160.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal

C8A Antibody - CSB-PA004194ESR1HU from Cusabio

Host Rabbit
Clonality Polyclonal

C8 α Polyclonal Antibody - 46913 from Signalway Antibody

Prices $189.00, $279.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of 1,mouse-kidney 2,mouse-heart cells using primary antibody diluted at 1:500(˚C overnight). Secondary antibody£ºGoat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25¡ãC, 1 hour)

Anti-C8 α antibody - STJ99337 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

anti-C8A antibody - A001139 from Biobool

Host Rabbit
Clonality Polyclonal

Complement Component 8a (C8a), Polyclonal Antibody - MBS2072940 from MyBioSource

Prices $925.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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