C8A

Gene Symbol	C8A
Entrez Gene	731
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	complement component 8, alpha polypeptide
Other Description	complement component 8 subunit alpha|complement component C8 alpha chain
Swissprots	Q13668 A2RUI4 P07357 A2RUI5 Q9H130
Accessions	AAA82124 EAX06644 EAX06645 EAX06646 P07357 AK309596 BC020702 AAH20702 BC132911 AAI32912 BC132913 AAI32914 HQ258328 ADR83082 M16974 AAA52200 XM_011542079 XP_011540381 NM_000562 NP_000553
Function	Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. {ECO:0000269|PubMed:17872444, ECO:0000269|PubMed:7440581}.
Subcellular Location	Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein. Inserts into the cell membrane of target cells.
Top Pathways	Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C8A Gene cDNA Clone - orb142124 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

C8A - MBS1275248 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC132913

C8A - MBS1278944 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC132911

Human C8A ORF Clone(NM_000562.2) - CDCL157045 from Creative Biomart Species Human Accession NM_000562.2

Human C8A Gene ORF cDNA clone in cloning vector - HG13985-G from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid - HG13985-UT from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid, C-HA tag - HG13985-CY from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13985-ACG from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid, N-His tag - HG13985-NH from Sino Biological Species Human

Human C8A Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG13985-NF from Sino Biological Species Human Accession BC132913

Human C8A Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13985-NM from Sino Biological Species Human

Human C8A natural ORF mammalian expression plasmid, C-OFPSpark / RFP tag - HG13985-ACR from Sino Biological Species Human Accession BC132913

Human C8A Gene ORF cDNA clone expression plasmid, C-His tag - HG13985-CH from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13985-CF from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid, N-HA tag - HG13985-NY from Sino Biological Species Human

Human C8A Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13985-CM from Sino Biological Species Human

Human C8A ORF Clone (BC132913) - CDCS405746 from Creative biogene Species Human Accession P07357

Human C8A ORF Clone (BC132911) - CDCS405747 from Creative biogene Species Human Accession P07357

Human C8A ORF clone (BC132913) - CDCB159496 from Creative biogene Species Human

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