RELA

Gene Symbol RELA
Entrez Gene 5970
Alt Symbol NFKB3, p65
Species Human
Gene Type protein-coding
Description v-rel avian reticuloendotheliosis viral oncogene homolog A
Other Description NF-kappa-B p65delta3|nuclear factor NF-kappa-B p65 subunit|nuclear factor of kappa light polypeptide gene enhancer in B-cells 3|transcription factor p65|v-rel reticuloendotheliosis viral oncogene homolog A
Swissprots Q04206 Q6GTV1 Q6SLK1
Accessions AAR13863 CAA80524 CCO13802 EAW74424 EAW74425 EAW74426 Q04206 AK303262 BAG64344 AK308020 AK308478 BC011603 AAH11603 BC014095 AAH14095 BC033522 AAH33522 BC069248 BC110830 AAI10831 BM916512 BU633061 DA020095 L19067 AAA20946 M62399 AAA36408 U33838 AAA92888 U88316 AAB48487 XM_011545206 XP_011543508 XM_011545207 XP_011543509 NM_001145138 NP_001138610 NM_001243984 NP_001230913 NM_001243985 NP_001230914 NM_021975 NP_068810
Function NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with ot
Subcellular Location Nucleus. Cytoplasm. Note=Colocalized with DDX1 in the nucleus upon TNF-alpha induction (By similarity). Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B). Colocalizes with GFI1 in the nucleus after LPS stimulation. {ECO:0000250}.
Top Pathways Sphingolipid signaling pathway, Apoptosis, Herpes simplex infection, Prolactin signaling pathway, Legionellosis

Human-RELA-cDNA-Clone - DC03759 from Abgent, a WuXi AppTec company

Prices $508.95
Sizes 10 µg
Species Human
Accession BC110830

Human RELA cDNA clone(NM_001145138.1) - CDFH016149 from Creative Biomart

Species Human
Accession NM_001145138.1

Human RELA ORF Clone(NM_001145138.1) - CDCR352426 from Creative Biomart

Species Human
Accession NM_001145138.1

human RELA ORF clone (NM_001243984.1) - CDCH072888 from Creative biogene

Species Human

human RELA ORF clone (NM_001243985.1) - CDCH072894 from Creative biogene

Species Human

human RELA ORF clone (NM_001145138.1) - CDCH072898 from Creative biogene

Species Human

human RELA ORF clone (NM_021975.3) - CDCH072900 from Creative biogene

Species Human

Human RELA ORF Clone (BC014095) - CDCS408456 from Creative biogene

Species Human
Accession Q04206

Human RELA ORF Clone (BC011603) - CDCS408457 from Creative biogene

Species Human
Accession Q04206

Human RELA ORF clone (NM_021975) - CDCB160281 from Creative biogene

Species Human

Human RELA cDNA Clone(NM_001145138.1) - CDFH016149 from Creative biogene

Species Human
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