| Gene Symbol |
CLCF1
|
| Entrez Gene |
23529
|
| Alt Symbol |
BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cardiotrophin-like cytokine factor 1
|
| Other Description |
B-cell stimulating factor 3|B-cell stimulatory factor 3|B-cell-stimulating factor 3|CRLF1 associated cytokine-like factor 1|neurotrophin-1/B-cell stimulating factor-3|novel neurotrophin-1
|
| Swissprots |
Q9UBD9 B4DNT4 Q6NZA4
|
| Accessions |
AAF00992 CAV33841 EAW74601 EAW74602 Q9UBD9 AF172854 AAD54284 AF176911 AAF00991 AK298052 BAG60346 AY049779 AAL15436 BC012939 AAH12939 BC066229 AAH66229 BC066230 AAH66230 BC066231 AAH66231 BM846622 DC393345 DQ891525 ABM82451 DQ894715 ABM85641 NM_001166212 NP_001159684 NM_013246 NP_037378
|
| Function |
Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor. {ECO:0000269|PubMed:10448081, ECO:0000269|PubMed:10500198}.
|
| Subcellular Location |
Secreted {ECO:0000250}.
|
| Tissue Specificity |
Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver. {ECO:0000269|PubMed:10448081, ECO:0000269|PubMed:10500198}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
|
![Western Blot: NR6 Overexpression Lysate (Adult Normal) [NBL1-09231] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NR6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6545_NR6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09231-img0002.jpg)