Gene Symbol | CLCF1 |
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Entrez Gene | 23529 |
Alt Symbol | BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 |
Species | Human |
Gene Type | protein-coding |
Description | cardiotrophin-like cytokine factor 1 |
Other Description | B-cell stimulating factor 3|B-cell stimulatory factor 3|B-cell-stimulating factor 3|CRLF1 associated cytokine-like factor 1|neurotrophin-1/B-cell stimulating factor-3|novel neurotrophin-1 |
Swissprots | Q9UBD9 B4DNT4 Q6NZA4 |
Accessions | AAF00992 CAV33841 EAW74601 EAW74602 Q9UBD9 AF172854 AAD54284 AF176911 AAF00991 AK298052 BAG60346 AY049779 AAL15436 BC012939 AAH12939 BC066229 AAH66229 BC066230 AAH66230 BC066231 AAH66231 BM846622 DC393345 DQ891525 ABM82451 DQ894715 ABM85641 NM_001166212 NP_001159684 NM_013246 NP_037378 |
Function | Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor. {ECO:0000269|PubMed:10448081, ECO:0000269|PubMed:10500198}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver. {ECO:0000269|PubMed:10448081, ECO:0000269|PubMed:10500198}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Human NNT1 full length protein - ab111634 from Abcam
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Human NNT1 full length protein - ab50021 from Abcam
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CLC Antibody Blocking Peptide - LS-E3281 from LifeSpan Bioscience
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CLC Antibody Blocking Peptide - LS-E3927 from LifeSpan Bioscience
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CLCF1 Antibody Blocking Peptide - LS-E6149 from LifeSpan Bioscience
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NR6/CLC Recombinant Protein - H00023529-P01 from Novus Biologicals
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Galectin-10 Partial Recombinant Protein - H00001178-Q01 from Novus Biologicals
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Recombinant Human Galectin-10 Protein - NBP1-51096 from Novus Biologicals
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Recombinant Human NR6/CLC Protein - NBP1-72423 from Novus Biologicals
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Recombinant Human Galectin-10 Protein - P3578 from Novus Biologicals
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CLCF1-Antibody-N-term-Blocking-Peptide - BP18774a from Abgent, a WuXi AppTec company
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NNT1 Protein - GTX109107-pro from GeneTex
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NNT1 Recombinant Protein (Active) - GTX48280-PRO from GeneTex
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Recombinant Human CLC - 962-CL-050 from R&D Systems
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Recombinant Human CLC, CF - 962-CL-050/CF from R&D Systems
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Recombinant Human CLC/CNTF R alpha Chimera - 2415-CR-025 from R&D Systems
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Recombinant Human CLC/CNTF R alpha Chimera, CF - 2415-CR-025/CF from R&D Systems
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Human CLCF1 protein - orb138561 from Biorbyt
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Human CLCF1 protein - orb168125 from Biorbyt
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CLCF1 protein (His tag) - 80R-1939 from Fitzgerald
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NNT1 protein - 30R-AN041 from Fitzgerald
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Human CLCF1 Protein - abx065731 from Abbexa
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CLCF1 (28-225, His-tag) - AR39121PU-L from Acris Antibodies
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CLCF1 (28-225, His-tag) - AR39121PU-N from Acris Antibodies
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CLCF1 - PA194 from Acris Antibodies
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