Uchl1

Gene Symbol Uchl1
Entrez Gene 22223
Alt Symbol AW822034, C88048, PGP 9.5, PGP9.5, R75593, UCH-L1, UCHL-1, gad
Species Mouse
Gene Type protein-coding
Description ubiquitin carboxy-terminal hydrolase L1
Other Description gracile axonal dystrophy|neuron cytoplasmic protein 9.5|protein gene product 9.5|ubiquitin carboxyl-terminal hydrolase isozyme L1|ubiquitin thioesterase L1
Swissprots Q9R0P9 Q9R122
Accessions EDL37772 EDL37773 Q9R0P9 AB025313 BAA84083 AF172334 AAD51029 AK004066 AK013729 BAB28976 AK170728 BAE41984 BC039177 AAH39177 CX241178 JX050004 AFP20215 NM_011670 NP_035800
Function Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. {ECO:0000269|PubMed:12913066}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12913066}. Endoplasmic reticulum membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Tissue Specificity Expressed in brain, where it is found in neurons but not in oligodendrocytes or astrocytes. Found in the ganglion cell layer and the inner nuclear layer of the retina (at protein level). Expressed in brain and testis. In the brain, expression is at its lowest in replaceable neurons of hippocampus and olfactory bulb. Highly expressed in senescent pituitary. {ECO:0000269|PubMed:10471497, ECO:0000269|PubMed:12559414, ECO:0000269|PubMed:12913066, ECO:0000269|PubMed:14695319, ECO:0000269|PubMed:15911766}.

UCH-L1/PGP9.5 Antibody - NBP1-51164 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PGP9.5 / UCHL-1 Antibody [NBP1-51164] - PGP9.5 / UCHL-1 Antibody Extracts from Rat liver tissues and mouse brain tissues.

PGP9.5 antibody - 70R-30722 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

UCHL1 antibody - orb171066 from Biorbyt

Prices $383.00, $604.00
Sizes 50 μg, 100 μg
Host Rabbit
Clonality Monoclonal

UCHL1 Antibody - abx104207 from Abbexa

Host Rabbit
Clonality Polyclonal

Mouse Anti-Human UCH-L1 - 129-10667 from RayBiotech

Host Mouse

Rabbit Anti-Human PGP9.5 - DS-PB-01677 from RayBiotech

Host Rabbit

Anti-UCHL1 antibody - STJ72312 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

Anti-UCHL1 antibody - STJ72313 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

PGP9.5 (clone 3D9), Antibody - GWB-A3E4F6 from Genway Biotech

Prices $185.00, $310.00
Sizes 50 μl, 100 μl
Host Mouse
Clonality Monoclonal
Clone Anti-human PGP9.5 mAb, clone 3D9, is derived

PGP9.5 Antibody - TGB-778 from Reagent Proteins

Prices $348.00, $675.00
Sizes 20.00 µg, 100.00 µg
Host Mouse
Clonality Monoclonal

UCHL1 Antibody, Rabbit MAb - 50690-R011-50 from Sino Biological

Prices $119.00, $119.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Monoclonal
Clone 011

UCHL1 Antibody, Rabbit PAb, Antigen Affinity Purified - 50690-RP02-50 from Sino Biological

Prices $99.00, $99.00, $99.00
Sizes 50 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

UCHL1 Antibody, Rabbit PAb - 50690-RP01-100 from Sino Biological

Prices $99.00, $99.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

UCHL1 Antibody, Rabbit MAb - 50690-R006-50 from Sino Biological

Prices $119.00, $119.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Monoclonal
Clone 006

UCHL 1 - 233 002 from Synaptic Systems

Host Rabbit
Clonality Polyclonal
Cat. No. 233 002 antibody dilution: 1 : 1000 sample: rat brain homogenate

UCHL 1 - 233 003 from Synaptic Systems

Host Rabbit
Clonality Polyclonal
Cat. No. 233 003 antibody dilution: 1 : 1000 sample: rat brain homogenate

UCHL1 antibody [DyLight 650] - pab51868 from Covalab

Host Rabbit
Clonality Polyclonal

UCHL1 antibody [DyLight 550] - pab51871 from Covalab

Host Rabbit
Clonality Polyclonal

PGP9.5 antibody - 70R-50526 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GAD1 antibody - 70R-49775 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PGP9.5 antibody - 70R-50527 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

anti-UCHL1 antibody - ARG65300 from Arigo Biolaboratories

ARG65300 anti-UCHL1 antibody WB image Western Blot: Human Hippocampus lysate (35 µg protein in RIPA buffer) stained with ARG65300 anti-UCHL1 (aa 58-68) antibody at 0.01 µg/ml dilution.
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