Uchl1

Gene Symbol	Uchl1
Entrez Gene	22223
Alt Symbol	AW822034, C88048, PGP 9.5, PGP9.5, R75593, UCH-L1, UCHL-1, gad
Species	Mouse
Gene Type	protein-coding
Description	ubiquitin carboxy-terminal hydrolase L1
Other Description	gracile axonal dystrophy|neuron cytoplasmic protein 9.5|protein gene product 9.5|ubiquitin carboxyl-terminal hydrolase isozyme L1|ubiquitin thioesterase L1
Swissprots	Q9R0P9 Q9R122
Accessions	EDL37772 EDL37773 Q9R0P9 AB025313 BAA84083 AF172334 AAD51029 AK004066 AK013729 BAB28976 AK170728 BAE41984 BC039177 AAH39177 CX241178 JX050004 AFP20215 NM_011670 NP_035800
Function	Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. {ECO:0000269|PubMed:12913066}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12913066}. Endoplasmic reticulum membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Tissue Specificity	Expressed in brain, where it is found in neurons but not in oligodendrocytes or astrocytes. Found in the ganglion cell layer and the inner nuclear layer of the retina (at protein level). Expressed in brain and testis. In the brain, expression is at its lowest in replaceable neurons of hippocampus and olfactory bulb. Highly expressed in senescent pituitary. {ECO:0000269|PubMed:10471497, ECO:0000269|PubMed:12559414, ECO:0000269|PubMed:12913066, ECO:0000269|PubMed:14695319, ECO:0000269|PubMed:15911766}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Mouse His6-UCH-L1, CF - E-335-025 from R&D Systems Category Protein Source E. coli-derived, Contains a 6-His tag

UCHL1 protein - 80R-4227 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

Mouse UCHL1 Protein - abx069586 from Abbexa Category Protein Source E.coli Species Mouse

UCHL1 / PGP9.5 (1-223, His-tag) - AR51909PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Mouse

UCHL1 / PGP9.5 (1-223, His-tag) - AR51909PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Mouse

Recombinant Mouse Uchl1, His-tagged - Uchl1-69M from Creative Biomart Category Protein Source E.coli Species Mouse

Recombinant Mouse Uchl1, His tagged - Uchl1-20M from Creative Biomart Category Protein Source E. coli Species Mouse

Mouse UCHL1 / PGP9.5 Protein (His Tag) - 50690-M07E-100 from Sino Biological Category Protein Prices $108.00, $108.00, $108.00 Sizes 20 µg, 100 µg, 200 µg Source E. coli Species Mouse

Recombinant Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) - RPG945Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) - RPG945Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase isozyme L1(Uchl1) - CSB-YP889925MO CSB-EP889925MO CSB-BP889925MO CSB-MP889925MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Uchl1, 1-223aa, Mouse, His tag, E.coli - ATGP3089 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Mouse

Recombinant Mouse His6-UCH-L1 Protein, CF - E-335 from R&D Systems Category Protein Prices $125.00 Sizes 25 µg Source E. coli -derived Contains a 6-His tag Species Mouse

Recombinant Mouse UCHL1 / PGP9.5 Protein (His tag) - PKSM040546 from Elabscience Category Protein Source E. coli Species Mouse

Recombinant Mouse UCHL1 Protein - UCHL1-17778M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Recombinant Mouse UCH-L1/PGP9.5 Protein - NBP2-52092 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 100 µg, 500 µg Source E.coli

Uchl1 - PAT-82942-2 from Nordic BioSite Category Protein Species Mouse

Uchl1 - PAT-82942-1 from Nordic BioSite Category Protein Species Mouse

Uchl1, 1-223aa, Mouse, His-tag, E.coli (Bioactivity Validated) - ATGP3568 from ATGen Category Protein Prices $30.00, $105.00, $320.00 Sizes 4 µg, 20 µg, 100 µg Species Mouse

UCHL1 Recombinant Protein (OPCD07799) - OPCD07799 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Mouse UCHL1 / PGP9.5 Protein (His Tag) - 50690-M07E from ABclonal Category Protein Prices $58.00, $108.00, $198.00 Sizes 20 µg, 100 µg, 200 µg Source E. coli Species Mouse

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