MAP3K14

Gene Symbol	MAP3K14
Entrez Gene	9020
Alt Symbol	FTDCR1B, HS, HSNIK, NIK
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 14
Other Description	NF-kappa-beta-inducing kinase|serine/threonine-protein kinase NIK
Swissprots	D3DX67 A8K2D8 Q8IYN1 Q99558
Accessions	ABC40733 EAW51529 EAW51530 Q99558 AA564389 AJ008135 AJ008136 AJ008137 AJ008138 AJ008139 AJ008140 AJ008141 AJ008142 AJ008143 AJ008144 AJ008145 AJ008146 AJ008147 AJ008148 AJ008149 AJ008150 AJ008151 AJ008152 AJ008153 AJ008156 AJ008157 AJ008158 AJ008159 AJ008160 AJ008161 AJ008162 AJ008163 AK123696 AK131438 BAD18584 AK290203 BAF82892 AK313085 BC022296 BC035576 AAH35576 BE645094 BU623799 CR749592 CAH18391 DA856801 DQ894064 ABM84990 HY096069 HY287427 Y10256 CAA71306 XM_011525441 XP_011523743 XR_934591 XR_951536 XR_952490 NM_003954 NP_003945
Function	Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non- canonical pathway. Could act in a receptor-selective manner. {ECO:0000269|PubMed:15084608}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon. {ECO:0000269|PubMed:9020361}.
Top Pathways	TNF signaling pathway, Apoptosis, Epstein-Barr virus infection, HTLV-I infection, Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cortisol (HS), Human, ELISA - IB79307 from ARP American Research Products Category ELISA Kit Prices $489.00 Sizes 96 t Sensitivity 0.012 ng/mL Range 0 / 0.1 - 30 ng/mL

Heparan sulfate, HS, General, ELISA Kit - E0623Ge from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 4.69-300 ng/mL

HS - MBS2515971 from MyBioSource Category ELISA Kit Sensitivity 0.188ng/mL Range 0.313--20ng/mL

mitogen-activated protein kinase kinase kinase 14, ELISA Kit - MBS9341552 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human HS(Heparan Sulfate) ELISA Kit - E-EL-H2364 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mLng/mL Range 0.31~20 ng/mL

Human HS(Heparan Sulfate) ELISA Kit - E-EL-H2364 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

HS - EKH8020 from Nordic BioSite Sensitivity 46.9ng/ml Range 78-5000ng/ml

Human HS ELISA Kit - E018244 from Biobool Category ELISA Kit Sensitivity Up to 5pg/ml.

Human MAP3K14 ELISA Kit - E024745 from Biobool Category ELISA Kit

General Heparan sulfate ELISA Kit - EK2043 from Signalway Antibody Category ELISA Kit Prices $659.00 Sizes 1x96t Range 4.69-300 ng/mL

anti-NIK antibody - ARG20457 from Arigo Biolaboratories Category ELISA Kit

anti-NIK antibody - ARG54322 from Arigo Biolaboratories Category ELISA Kit

Human HS ELISA Kit - E018237 from Biobool Category ELISA Kit Sensitivity 1.17 ng/mL

HS (Heparan Sulfate), ELISA Kit - MBS766118 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.9ng/ml Range 78-5000ng/ml

Human HS (Heparan Sulfate) ELISA Kit - EKE61286 from Biomatik Category ELISA Kit Prices $609.00 Sizes 96 tests Sensitivity 0.19 ng/mL Range 0.31-20 ng/mL

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