MAP3K14

Gene Symbol	MAP3K14
Entrez Gene	9020
Alt Symbol	FTDCR1B, HS, HSNIK, NIK
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 14
Other Description	NF-kappa-beta-inducing kinase|serine/threonine-protein kinase NIK
Swissprots	D3DX67 A8K2D8 Q8IYN1 Q99558
Accessions	ABC40733 EAW51529 EAW51530 Q99558 AA564389 AJ008135 AJ008136 AJ008137 AJ008138 AJ008139 AJ008140 AJ008141 AJ008142 AJ008143 AJ008144 AJ008145 AJ008146 AJ008147 AJ008148 AJ008149 AJ008150 AJ008151 AJ008152 AJ008153 AJ008156 AJ008157 AJ008158 AJ008159 AJ008160 AJ008161 AJ008162 AJ008163 AK123696 AK131438 BAD18584 AK290203 BAF82892 AK313085 BC022296 BC035576 AAH35576 BE645094 BU623799 CR749592 CAH18391 DA856801 DQ894064 ABM84990 HY096069 HY287427 Y10256 CAA71306 XM_011525441 XP_011523743 XR_934591 XR_951536 XR_952490 NM_003954 NP_003945
Function	Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non- canonical pathway. Could act in a receptor-selective manner. {ECO:0000269|PubMed:15084608}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon. {ECO:0000269|PubMed:9020361}.
Top Pathways	TNF signaling pathway, Apoptosis, Epstein-Barr virus infection, HTLV-I infection, Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human NFkB Inducing Kinase NIK protein fragment - ab105210 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Human NFkB Inducing Kinase NIK protein fragment - ab160294 from Abcam Category Protein Source Wheat germ Species Human

Human NIK full length protein - ab132206 from Abcam Category Protein Source Wheat germ Species Human

NFkB Inducing Kinase NIK peptide - ab8385 from Abcam Category Peptide

NFkB Inducing Kinase NIK protein fragment - ab61262 from Abcam Category Protein Source Baculovirus infected sf9 cells

MAP3K14 Antibody Blocking Peptide - LS-E3024 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP3K14 Antibody Blocking Peptide - LS-E9397 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP3K14 Antibody Blocking Peptide - LS-E15514 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP3K14 Antibody Blocking Peptide - LS-E29846 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NIK/MAP3K14 Recombinant Protein - H00009020-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

NIK/MAP3K14 Partial Recombinant Protein - H00009020-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NIK/MAP3K14 Protein - P4734 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Source Insect Species Human

NIK/MAP3K14 Blocking Peptide - NBP1-76476PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

NIK/MAP3K14 Peptide - P2961 from Novus Biologicals Category Peptide Species Human

NIK-Antibody-Center-Blocking-Peptide - BP7967c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K14 peptide - GTX28385 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

MAP3K14 Blocking Peptide - 33R-8382 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NIK Blocking Peptide - 33R-10665 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

MAP3K14 - H00009020-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

MAP3K14 - H00009020-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAP3K14 - H00009020-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAP3K14 - P4734 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

MAP3K14 - P5725 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

MAP3K14 Control Peptide - AP30595CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NIK Peptide - 1129P from ProSci Category Peptide Species Human

Search more