CTSD

Gene Symbol CTSD
Entrez Gene 1509
Alt Symbol CLN10, CPSD, HEL-S-130P
Species Human
Gene Type protein-coding
Description cathepsin D
Other Description ceroid-lipofuscinosis, neuronal 10|epididymis secretory sperm binding protein Li 130P|lysosomal aspartyl peptidase|lysosomal aspartyl protease
Swissprots Q6IB57 P07339
Accessions AAA16314 AAA51922 AAD13868 AAD14156 EAX02461 EAX02462 EAX02463 P07339 AK130178 BC001574 BC016320 AAH16320 BM762986 BM976200 BT006910 AAP35556 BT020155 AAV38957 CR456947 CAG33228 DQ893547 ABM84473 DQ893878 ABM84804 EU794598 ACJ13652 M11233 AAB59529 X05344 CAA28955 NM_001909 NP_001900
Function Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Subcellular Location Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380). {ECO:0000269|PubMed:20551380}.
Tissue Specificity Expressed in the aorta extrcellular space (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways Lysosome, Tuberculosis, Sphingolipid signaling pathway

Active human Cathepsin D full length protein - ab91123 from Abcam

Category Protein
Prices $356.00
Sizes 25 µg
Source Native
Species Human
SDS-PAGE: 4-12% Bis-Tris NuPAGE gel Lane 1. Molecular weight markers Lane 2. 4 µg Cathepsin D (non-reduced/no heat) Lane 3. 7 µg Cathepsin D (non-reduced/no heat) Lane 4. Molecular weight markers Lane 5. 4 µg Cathepsin D (reduced/heated) Lane 6. 7 µg Cathepsin D (reduced/heated)

Active human Cathepsin D full length protein - ab77871 from Abcam

Category Protein
Prices $356.00
Sizes 25 µg
Source Native
Species Human

Active human proCathepsin D full length protein - ab191632 from Abcam

Category Protein
Prices $597.00
Sizes 50 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of reduced ab191632 stained overnight with Coomassie Blue. DTT-reduced Protein migrates as 45-55 kDa due to glycosylation.

Cathepsin D peptide - ab90605 from Abcam

Category Peptide
Prices $176.00
Sizes 100 µg

Human Cathepsin D full length protein - ab38258 from Abcam

Category Protein
Prices $334.00
Sizes 10 µg
Source E. coli
Species Human

Human proCathepsin D full length protein - ab151860 from Abcam

Category Protein
Source HEK 293 cells
Species Human

Mouse Cathepsin D full length protein - ab191943 from Abcam

Category Protein
Source HEK 293 cells
Species Mouse

CTSD / Cathepsin D Antibody Blocking Peptide - LS-E10136 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CTSD / Cathepsin D Antibody Blocking Peptide - LS-E15270 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Cathepsin D Recombinant Protein - H00001509-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Cathepsin D Human Expressed Protein - P4030 from Novus Biologicals

Category Protein
Prices $499.00
Sizes 5 µg
Source Human
Species Human

Cathepsin D Human Expressed Protein - NBP1-99196 from Novus Biologicals

Category Protein
Prices $165.00
Sizes 5 µg
Source Human
Species Human

CTSD-Antibody-C-term-Blocking-Peptide - BP9447b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Cathepsin D, CF - 1014-AS-010 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Leu21-Leu412, with a C-terminal 10-His tag

Recombinant Mouse Cathepsin D, CF - 1029-AS-010 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Ile21-Leu410, with a C-terminal 10-His tag

CTSD Protein (OPPA01674) - OPPA01674 from Aviva Systems Biology

Category Protein
Prices $250.00
Sizes 2 µg
Source E. Coli

E.coli CTSD protein - orb246318 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Escherichia coli

Human CTSD protein - orb90059 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Source E.coli
Species Human

Human CTSD protein (His Tag) - orb138648 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 10 μg, 20 μg
Source Human Cells
Species Human
SDS-PAGE analysis of human CTSD protein (His Tag)

Human CPSD protein - orb245115 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human Cathepsin D protein - orb49252 from Biorbyt

Category Protein
Prices $366.00, $706.00, $2,321.00, $3,281.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Species Human

Human Cathepsin D protein - orb176084 from Biorbyt

Category Protein
Prices $425.00, $578.00
Sizes 2 μl, 10 μl

Human CPSD protein - orb245116 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Purified Human Cathepsin D protein - orb82125 from Biorbyt

Category Protein
Prices $281.00
Sizes 25 μg
Source Sample obtained from Human Liver.
Species Human

Cathepsin D Blocking Peptide - 33R-10663 from Fitzgerald

Category Peptide
Prices $145.00
Sizes 50 µg
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