CTSD

Gene Symbol CTSD
Entrez Gene 1509
Alt Symbol CLN10, CPSD, HEL-S-130P
Species Human
Gene Type protein-coding
Description cathepsin D
Other Description ceroid-lipofuscinosis, neuronal 10|epididymis secretory sperm binding protein Li 130P|lysosomal aspartyl peptidase|lysosomal aspartyl protease
Swissprots Q6IB57 P07339
Accessions AAA16314 AAA51922 AAD13868 AAD14156 EAX02461 EAX02462 EAX02463 P07339 AK130178 BC001574 BC016320 AAH16320 BM762986 BM976200 BT006910 AAP35556 BT020155 AAV38957 CR456947 CAG33228 DQ893547 ABM84473 DQ893878 ABM84804 EU794598 ACJ13652 M11233 AAB59529 X05344 CAA28955 NM_001909 NP_001900
Function Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Subcellular Location Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380). {ECO:0000269|PubMed:20551380}.
Tissue Specificity Expressed in the aorta extrcellular space (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways Lysosome, Tuberculosis, Sphingolipid signaling pathway

cathepsin D CRISPR/Cas9 KO Plasmid (h) - sc-400207 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D HDR Plasmid (h) - sc-400207-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D Double Nickase Plasmid (h) - sc-400207-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D Double Nickase Plasmid (h2) - sc-400207-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D CRISPR Activation Plasmid (h) - sc-400207-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D CRISPR Activation Plasmid (h2) - sc-400207-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D Lentiviral Activation Particles (h) - sc-400207-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D Lentiviral Activation Particles (h2) - sc-400207-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cathepsin D siRNA (h) - sc-29239 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cathepsin D shRNA Plasmid (h) - sc-29239-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cathepsin D shRNA (h) Lentiviral Particles - sc-29239-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cathepsin D RNAi - H00001509-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU040951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2029 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2029 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07351 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07351

CTSD siRNA (Human) - CRH1066 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTSD - MBS8239242 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CTSD (NM_001909.4) - SHH271517 from Creative biogene

Category siRNA
Species Reactivities Human

Human CTSD siRNA - orb261568 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTSD shRNA Plasmid (Human) - CHH1066 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CTSD miRNA 3'UTR clone - MiUTR3H-00375 from Creative biogene

Species Reactivities Human
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