A1CF

Gene Symbol A1CF
Entrez Gene 29974
Alt Symbol ACF, ACF64, ACF65, APOBEC1CF, ASP
Species Human
Gene Type protein-coding
Description APOBEC1 complementation factor
Other Description APOBEC-1 stimulating protein|apo-B RNA editing protein|apobec-1 complementation factor (ACF) (ASP)
Swissprots Q9NZD3 A8K7G7 A1L4F2 Q9NXC9 Q5SZQ0 Q9NQ93 Q9NQ94 Q9NQX8 Q9NQX9 B7ZM14
Accessions EAW54133 EAW54134 EAW54135 EAW54136 EAW54137 EAW54138 Q9NQ94 AF209192 AAF34824 AF271789 AAF76221 AF271790 AAF76222 AJ272078 CAB94754 AJ272079 CAB94755 AK000324 BAA91086 AK130022 AK291982 BAF84671 AK303801 BAG64755 BC022263 BC054873 AAH54873 BC130519 AAI30520 BC144194 BC144196 AAI44197 BG188383 CR749831 XM_005269718 XP_005269775 XM_005269720 XP_005269777 XM_011539729 XP_011538031 XM_011539730 XP_011538032 NM_001198818 NP_001185747 NM_001198819 NP_001185748 NM_001198820 NP_001185749 NM_014576 NP_055391 NM_138932 NP_620310 NM_138933 NP_620311
Function Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. {ECO:0000269|PubMed:10669759, ECO:0000269|PubMed:10781591, ECO:0000269|PubMed:12881431}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12881431}. Endoplasmic reticulum {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:12881431}. Note=Predominantly nuclear where it localizes to heterochromatin. Also cytoplasmic where it is found at the outer surface of the endoplasmic reticulum (By similarity). Shuttles between the nucleus and cytoplasm. May be transported into the nucleus by the nuclear import protein TNPO2/TRN2 or by APOBEC1. {ECO:0000250}.
Tissue Specificity Widely expressed with highest levels in brain, liver, pancreas, colon and spleen. {ECO:0000269|PubMed:10669759}.

A1CF / ACF Antibody Blocking Peptide - LS-E392 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

A1CF / ACF Antibody Blocking Peptide - LS-E14945 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

A1CF / ACF Antibody Blocking Peptide - LS-E15094 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ACF-Antibody-C-term-Blocking-peptide - BP10670b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

A1CF Blocking Peptide - 33R-5962 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

A1CF Blocking Peptide - 33R-2286 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

A1CF fusion protein - Ag22975 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50
Source E. coli -derived, PET30a
Species Human

Recombinant Apobec 1 Complementation Factor (ACF) - RPA426Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Human APOBEC1 complementation factor(A1CF) - CSB-YP001002HU CSB-EP001002HU CSB-BP001002HU CSB-MP001002HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

APOBEC1 complementation factor (transcript variant 2) - TP316861 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
APOBEC1 complementation factor

APOBEC1 complementation factor (transcript variant 3) - TP316911 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
APOBEC1 complementation factor

APOBEC1 complementation factor (A1CF) , Recombinant Protein - MBS1416439 from MyBioSource

Category Protein
Prices $2,330.00, $2,330.00, $2,755.00, $2,755.00
Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

A1CF Recombinant Protein (OPCD01028) - OPCD01028 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human

Recombinant Human A1CF Protein, His-tagged - A1CF-641H from Creative Biomart

Category Protein
Source E. coli
Species Human
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