Gene Symbol | Tln1 |
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Entrez Gene | 21894 |
Alt Symbol | Tln |
Species | Mouse |
Gene Type | protein-coding |
Description | talin 1 |
Other Description | talin-1 |
Swissprots | P26039 Q8VEF0 A2AIM8 |
Accessions | EDL02465 EDL02466 EDL02467 P26039 AK006088 AK040128 BAC30516 AK122420 BAC65702 AK147228 BAE27781 AK170630 BAE41923 AK171322 BAE42391 AK190044 BC018557 AAH18557 BC050080 BC055348 BC059711 BC121787 AAI21788 BC150810 AAI50811 CJ242702 X56123 CAA39588 XM_006537768 XP_006537831 XM_006537769 XP_006537832 XM_006537770 XP_006537833 XM_006537771 XP_006537834 NM_011602 NP_035732 |
Function | Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. |
Subcellular Location | Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell surface {ECO:0000269|PubMed:21768292}. Cell junction, focal adhesion {ECO:0000269|PubMed:21768292}. Note=Colocalizes with LAYN at the membrane ruffles (By similarity). Localized preferentially in focal adhesions than fibrillar adhesions. {ECO:0000250}. |
Top Pathways | Focal adhesion, HTLV-I infection, Rap1 signaling pathway |
Talin-1, Tln1, Mouse, ELISA Kit - E2104m from ARP American Research Products
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ELISA Kit for Talin (TLN) - SEA278Mu from Cloud-clone
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Mouse Talin-1 ELISA Kit - EKE53411 from Biomatik
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Mouse Tln1 ELISA Kit - E069537 from Biobool
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Tln1 ELISA Kit (Mouse) (OKEH04776) - OKEH04776 from Aviva Systems Biology
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Talin (TLN), ELISA Kit - MBS452198 from MyBioSource
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