BEX2

Gene Symbol BEX2
Entrez Gene 84707
Alt Symbol BEX1, DJ79P11.1
Species Human
Gene Type protein-coding
Description brain expressed X-linked 2
Other Description brain-expressed X-linked protein 2|hBex2|protein BEX2
Swissprots Q5JVV9 B2R574 D3DXA2 F5H7H5 Q9BXY8
Accessions CAD24039 EAW54715 EAW54716 Q9BXY8 AF251053 AAK34943 AK312085 BAG35021 AY833560 AAX40678 BC015522 AAH15522 BC050651 BI670202 BU569325 BU596902 CB961647 CD365521 CK001963 DB498563 NM_001168399 NP_001161871 NM_001168400 NP_001161872 NM_001168401 NP_001161873 NM_032621 NP_116010
Function Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. {ECO:0000269|PubMed:19711341}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:16314316}.
Tissue Specificity Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines. {ECO:0000269|PubMed:15958283, ECO:0000269|PubMed:19711341}.

Bex1/2 (M-113) - sc-98915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Bex2 (C-12) - sc-398486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bex2 (C-12): sc-398486. Western blot analysis of Bex2 expression in non-transfected: sc-110760 (A) and human Bex2 transfected: sc-113220 (B) 293 whole cell lysates.

Bex2 (N-14) - sc-48966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Bex2 (N-14): sc-48966. Western blot analysis of Bex2 expression in non-transfected: sc-110760 (A) and human Bex2 transfected: sc-113220 (B) 293 whole cell lysates.

Bex2 (4H34) - sc-70421 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Bex2 (9E1237) - sc-52916 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-BEX2 antibody [9E1237] - ab13813 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 9E1237
ab13813 staining BEX2 in Human glioblastoma cell line 48 hours after Bex2 over-expression by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with 4% paraformaldehyde and blocked with 10% Goat serum. Samples were incubated with primary antibody, followed by a HRP-conjugated Goat anti-mouse IgG. Left - GFP treated, Middle - GFP-Bex2 treated, Right - untreated. Top row - Bex2 staining, Bottom row - GFP staining (left and middle), PBS control (right).

Anti-BEX2 Antibody - LS-C4158 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

BEX2 Antibody - NBP2-31553 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: BEX2 Antibody [NBP2-31553] - liver cancer

BEX2 Antibody - NBP2-33443 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: BEX2 Antibody [NBP2-33443] - Staining of human rectum shows moderate cytoplasmic positivity in glandular cells.

Anti-BEX2 (1-12) antibody produced in rabbit - SAB1104827 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human BEX2 was separated on SDS-PAGE, blotted with Anti-BEX2 (1-12) (<B>Cat. No. SAB1104827</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-BEX2 antibody produced in rabbit - HPA045384 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BEX2: <B>Cat. No. HPA045384</B>: Immunohistochemical staining of Human rectum shows moderate cytoplasmic positivity in glandular cells.

BEX1/2 antibody [N3C3] - GTX108673 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal

BEX2 antibody [9E1237] - GTX13813 from GeneTex

Prices $349.00
Sizes 100 μg
Host Mouse
Clonality Monoclonal
Clone 9E1237
Anti-BEX2 antibody [9E1237] used in Western blot. GTX13813

Anti -BEX1 (Brain Expressed X-linked Protein 1) - B1081-75 from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 8J324

Anti -BEX1, ID (BEX1, Protein BEX1, Brain-expressed X-linked protein 1) - 032500 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX1, ID (BEX1, Protein BEX1, Brain-expressed X-linked protein 1) (AP) - 032500-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX1, ID (BEX1, Protein BEX1, Brain-expressed X-linked protein 1) (APC) - 032500-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX1, ID (BEX1, Protein BEX1, Brain-expressed X-linked protein 1) (Biotin) - 032500-Biotin from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX1, ID (BEX1, Protein BEX1, Brain-expressed X-linked protein 1) (FITC) - 032500-FITC from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX1, ID (BEX1, Protein BEX1, Brain-expressed X-linked protein 1) (PE) - 032500-PE from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX2 (Brain Expressed X-linked 2, BEX1, DJ79P11.1) - 209754 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -BEX2 (Brain Expressed X-linked 2, BEX1, HGR74) - B1090D from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 4H34

BEX2 antibody - 70R-15989 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

BEX2 Polyclonal Antibody - A5064 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
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