BEX2

Gene Symbol	BEX2
Entrez Gene	84707
Alt Symbol	BEX1, DJ79P11.1
Species	Human
Gene Type	protein-coding
Description	brain expressed X-linked 2
Other Description	brain-expressed X-linked protein 2|hBex2|protein BEX2
Swissprots	Q5JVV9 B2R574 D3DXA2 F5H7H5 Q9BXY8
Accessions	CAD24039 EAW54715 EAW54716 Q9BXY8 AF251053 AAK34943 AK312085 BAG35021 AY833560 AAX40678 BC015522 AAH15522 BC050651 BI670202 BU569325 BU596902 CB961647 CD365521 CK001963 DB498563 NM_001168399 NP_001161871 NM_001168400 NP_001161872 NM_001168401 NP_001161873 NM_032621 NP_116010
Function	Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. {ECO:0000269|PubMed:19711341}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:16314316}.
Tissue Specificity	Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines. {ECO:0000269|PubMed:15958283, ECO:0000269|PubMed:19711341}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Bex1 peptide - ab194751 from Abcam Category Peptide

Human Bex1 peptide - ab97992 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

BEX1 Antibody Blocking Peptide - LS-E420 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Bex1 Protein - NBP2-22718 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

BEX1 protein (His tag) - 80R-2883 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

BEX2 fusion protein - ag3066 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Protein BEX2(BEX2) - CSB-YP883628HU CSB-EP883628HU CSB-BP883628HU CSB-MP883628HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BEX2 (full length, N-term HIS tag, transcript variant 3) - TP760028 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

Human BEX1 protein - orb259808 from Biorbyt Category Protein Prices $170.00, $289.00, $1,122.00 Sizes 2 μg, 10 μg, 100 μg Species Human

BEX2 Recombinant Protein Antigen - NBP2-33443PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BEX1 Peptide, Human - M34GP01418H from Creative Peptides Category Peptide Source Synthetic. Species Human

BEX2 Peptide, Human - M34GP01419H from Creative Peptides Category Peptide Source Synthetic. Species Human

BEX2 Antibody - SH-A10587 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

BEX1 - PAT-82177-1 from Nordic BioSite Category Protein Species Human

BEX1 - PAT-82177-2 from Nordic BioSite Category Protein Species Human

Protein BEX2 (BEX2), Recombinant Protein - MBS1360663 from MyBioSource Category Protein Prices $865.00, $865.00, $1,090.00, $1,090.00, $1,260.00, $1,260.00, $1,715.00, $1,715.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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