PPP3CA

Gene Symbol	PPP3CA
Entrez Gene	5530
Alt Symbol	CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 3, catalytic subunit, alpha isozyme
Other Description	CAM-PRP catalytic subunit|calcineurin A alpha|calmodulin-dependent calcineurin A subunit alpha isoform|protein phosphatase 2B, catalytic subunit, alpha isoform|protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform|serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Swissprots	A1A441 A8W6Z8 B5BUA2 A8W6Z7 A8K3B7 Q8TAW9 Q08209
Accessions	EAX06123 EAX06124 EAX06125 Q08209 AB451338 BAG70152 AB451487 BAG70301 AK290532 BAF83221 AL353950 CAB89253 AM393486 CAL38363 AM393713 CAL38589 AW973358 AY904364 AAY17314 BC025714 AAH25714 BC098424 EU192652 ABW74484 EU192653 ABW74485 J05480 AAA35634 L14778 AAA02631 NM_000944 NP_000935 NM_001130691 NP_001124163 NM_001130692 NP_001124164
Function	Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. {ECO:0000269|PubMed:15671020, ECO:0000269|PubMed:17498738, ECO:0000269|PubMed:18838687}.
Subcellular Location	Cell membrane {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. {ECO:0000250}.
Top Pathways	Glucagon signaling pathway, Glutamatergic synapse, Dopaminergic synapse, Amphetamine addiction, Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Calcineurin (CaN), Human, ELISA Kit - SEB323Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

ELISA Kit for Calcineurin (CaN) - SEB323Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.062ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Calcineurin (CaN) - SEB323Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Calcineurin (CaN) - SEB323Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.104ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Calcineurin (CaN) - SEB323Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.062ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Calcineurin (CaN), Human, ELISA Kit - DL-CaN-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human PPP3CA ELISA Kit - E094109 from Biobool Category ELISA Kit

PPP3CA ELISA Kit (Human) (OKCD00274) - OKCD00274 from Aviva Systems Biology Category ELISA Kit Prices $525.00 Sizes 96 wells Sensitivity < 0.057 ng/mL Range 0.156-10 ng/mL

CaN ELISA Kit (Human) (OKDD00163) - OKDD00163 from Aviva Systems Biology Category ELISA Kit Prices $555.00 Sizes 96 wells Sensitivity < 0.055 ng/mL Range 0.156-10 ng/mL

Calcineurin (CaN), ELISA Kit - MBS455514 from MyBioSource Category ELISA Kit Prices $400.00, $530.00, $2,325.00, $4,515.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.055ng/mL Range 0.156-10ng/mL

Calcineurin (CaN), DIY ELISA Kit - MBS2089078 from MyBioSource Category ELISA Kit Prices $585.00, $705.00, $930.00, $1,055.00 Sizes 5x96 tests, 5x96 tests + mbs2089471 (Support Pack 1), 10x96 tests, 10x96 tests + mbs2089471 (Support Pack 1) Sensitivity 0.104ng/mL Range 0.312-20ng/mL

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