Gene Symbol | C1qa |
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Entrez Gene | 12259 |
Alt Symbol | AI255395, C1q |
Species | Mouse |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent, alpha polypeptide |
Other Description | complement C1q subcomponent subunit A |
Swissprots | Q9DCM6 P98086 |
Accessions | EDL29926 P98086 AK002655 BAB22262 AK136737 BAE23115 AK150771 BAE29837 AK159210 BAE34901 AK159343 BAE35005 BC002086 AAH02086 BC020096 BY318890 BY698724 X58861 CAA41664 NM_007572 NP_031598 |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection |
C1q-A (E-15) - sc-27661 from Santa Cruz Biotechnology
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C1q-A (7H8) - sc-58920 from Santa Cruz Biotechnology
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Anti-C1q antibody - ab64632 from Abcam
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Anti-C1q antibody [4.8] - ab182451 from Abcam
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Complement Component C1qA Antibody (7H8) - NB200-539 from Novus Biologicals
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C1q antibody [7H8] - GTX54390 from GeneTex
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Anti -C1q (11S Protein) (Biotin) - C0010-10B from USBiological Life Science
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Anti -C1q (11S Protein) (FITC) - C0010-10A from USBiological Life Science
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Anti -C1q (C1qa, Complement Component 1, q Subcomponent, alpha Polypeptide, AI255395, C1q,Complement C1q Subcomponent Subunit A) - C0010-10C from USBiological Life Science
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C1q A subunit antibody - AM26328PU-N from Acris Antibodies
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C1q, Monoclonal Antibody - MBS584245 from MyBioSource
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C1q, Monoclonal Antibody - MBS584342 from MyBioSource
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C1q, Monoclonal Antibody - MBS584153 from MyBioSource
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C1q, Monoclonal Antibody - MBS584167 from MyBioSource
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C1q, Antibody - GWB-F0BE23 from Genway Biotech
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Complement C1q Antibody - GWB-4F32D0 from Genway Biotech
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Anti-C1QA (aa 50-150) polyclonal antibody - CPBT-28861RM from Creative Diagnostics
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Anti-C1QA monoclonal antibody, clone 5.9 - DCABH-7464 from Creative Diagnostics
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Anti-C1QA monoclonal antibody, clone KM-2 - DCABH-9532 from Creative Diagnostics
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Mouse anti-C1q Monoclonal antibody [clone KM-2], Biotin-Conjugated - DCABH-9540 from Creative Diagnostics
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C1q Monoclonal Antibody (7H8) - MA1-40045 from Thermo Fisher Scientific
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Sheep anti Complement C1q Antibody (1ml) - OAMA03455 from Aviva Systems Biology
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C1qA antibody - GTX134007 from GeneTex
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