CACNA1B

Gene Symbol	CACNA1B
Entrez Gene	774
Alt Symbol	BIII, CACNL1A5, CACNN, Cav2.2, DYT23
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, N type, alpha 1B subunit
Other Description	Cav2.2 voltage-gated Ca2+ channel|brain calcium channel III|calcium channel alpha12.2 subunit|calcium channel, L type, alpha-1 polypeptide|calcium channel, N type|calcium channel, voltage-dependent, L type, alpha 1B subunit|calcium channel, voltage-dependent, alpha 1B subunit, N type|voltage-dependent N-type calcium channel subunit alpha-1B|voltage-gated calcium channel alpha subunit Cav2.2|voltage-gated calcium channel subunit alpha Cav2.2
Swissprots	B1AQK5 Q00975
Accessions	AAC51138 AAG13642 AAG13643 AAG13644 AAG13645 AAG13646 AAG13647 AAG13648 AAG13650 AAG14396 AAG14397 AAG14398 CAJ41866 EAW88415 EAW88416 EAW88417 EAW88418 Q00975 AB209467 BAD92704 AY429522 AY429523 BC033060 M94172 AAA51897 M94173 AAA51898 XM_011518990 XP_011517292 XM_011518991 XP_011517293 XM_011518992 XP_011517294 XM_011518993 XP_011517295 XM_011518994 XP_011517296 XM_011518995 XP_011517297 XM_011518996 XP_011517298 XM_011518997 XP_011517299 NM_000718 NP_000709 NM_001243812 NP_001230741
Function	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin- IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Isoform Alpha-1b-1 and isoform Alpha-1b-2 are expressed in the central nervous system, but not in skeletal muscle or aorta.
Top Pathways	GABAergic synapse, Retrograde endocannabinoid signaling, Nicotine addiction, Morphine addiction, Dopaminergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse CACNA1B / Cav2.2 ELISA Kit (Sandwich ELISA) - LS-F8776 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.053 ng/ml Range 0.156-10 ng/ml

Human CACNA1B / Cav2.2 ELISA Kit (Sandwich ELISA) - LS-F9598 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.156-10 ng/ml

Human CACNa1B ELISA Kit - abx150886 from Abbexa Category ELISA Kit Sensitivity 0.129 ng/ml Range 0.313 ng/ml - 20 ng/ml

Calcium Channel, Voltage Dependent, N-Type, Alpha 1B Subunit (CACNa1B), Human, ELISA Kit - SEF240Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.129ng/mL Range 0.312-20ng/mL

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), Human, ELISA Kit - CSB-EL004398HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), Human, ELISA Kit - E01V0056 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

calcium channel, voltage-dependent, N type, alpha 1B subunit, ELISA Kit - MBS904215 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human CACNA1B is typically less than 6.25 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7250198 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7203101 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7235875 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7202362 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7211109 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7219609 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7252673 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7225332 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage dependent N type calcium channel subunit Alpha 1B (CACNA1B), ELISA Kit - MBS744329 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Voltage-dependent N-type calcium channel subunit Alpha 1B (CACNA1B), ELISA Kit - MBS7212089 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL

ELISA Kit for Calcium Channel, Voltage Dependent, N-Type, Alpha 1B Subunit (CACNa1B) - SEF240Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.129ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Calcium Channel, Voltage Dependent, N-Type, Alpha 1B Subunit (CACNa1B) - SEF240Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.053ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Voltage-dependent N-type calcium channel subunit alpha-1B(CACNA1B) ELISA kit - CSB-EL004398HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range Request Information

ELISA Kit for Calcium Channel, Voltage Dependent, N-Type, Alpha 1B Subunit (CACNa1B) - SEF240Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.129ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), ELISA Kit - MBS7243778 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human CACNa1B ELISA Kit - abx573172 from Abbexa Category ELISA Kit Sensitivity 0.129 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B) ELISA Kit - EKC36042 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

Human CACNA1B ELISA Kit - E006022 from Biobool Category ELISA Kit Sensitivity Typically less than 0.129ng/mL.

Search more