Ebi3

Gene Symbol Ebi3
Entrez Gene 50498
Alt Symbol EBI-3, IL-27
Species Mouse
Gene Type protein-coding
Description Epstein-Barr virus induced gene 3
Other Description IL-27 subunit beta|IL-27B|epstein-Barr virus-induced gene 3 protein homolog|interleukin-27 subunit beta
Swissprots O35228
Accessions EDL23692 EDL23693 O35228 AF013114 AAB67115 AK155023 BAE32996 AK155903 BAE33494 AW495532 BC008209 AAH08209 BI134394 BY134465 CX240802 XM_006524599 XP_006524662 NM_015766 NP_056581
Function Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T- helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Subcellular Location Secreted {ECO:0000250}.

Ebi3 (C-18) - sc-26802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Ebi3 (W-20) - sc-26800 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ebi3 (W-20): sc-26800. Western blot analysis of mouse recombinant Ebi3 fusion protein.

Anti-EBI3 antibody - ab92759 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of 100 ng of HEK 293 cells transfected with mouse EBI3 using 1ug/mL rabbit anti-mouse polyclonal antibody and anti-rabbit secondary on nitrocellulose.

Anti-EBI3 antibody - ab121041 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EBI3 antibody (ab121041) at 0.5 µg/mlLane 1 : RAW cell lysateLane 2 : RAW cell lysate with immunizing peptideLysates/proteins at 40 µg per lane.Secondarygoat anti-rabbit Ig HRPdeveloped using the ECL technique

Anti-EBI3 antibody (Biotin) - ab106031 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-EBI3 antibody (Biotin) (ab106031) at 1/2000 dilution + Mouse cell extract

IL-27/IL-35 EBI3 Subunit Antibody - NBP2-03944 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

IL-27/IL-35 EBI3 Subunit Antibody (10J803) - NBP2-03940 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 10J803
Western Blot: IL-27/IL-35 EBI3 Subunit Antibody (10J803) [NBP2-03940] - Analysis of mouse thymus tissue using EBI3 antibody at a concentration of 1 ug/ml.

IL-27/IL-35 EBI3 Subunit Antibody (10J763) - NBP2-03939 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 10J763

IL-27/IL-35 EBI3 Subunit Antibody (5P10D3) - NBP2-03943 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 5P10D3
Western Blot: EBI3 Antibody (5P10D3) [NBP2-03943] - Analysis using EBI3 antibody. Mouse EBI recombinant protein (A) and lysate from mouse kidney (B) probed with EBI3 antibody at 0.5 and 5 ug/ml, respectively. Goat anti-rat Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

IL-27/IL-35 EBI3 Subunit Antibody (5P6G8) - NBP2-03942 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 5P6G8
Western Blot: EBI3 Antibody (5P6G8) [NBP2-03942] - Analysis using EBI3 antibody. Mouse EBI recombinant protein (A) and lysate from mouse kidney (B) probed with EBI3 antibody at 0.5 and 5 ug/ml, respectively. Goat anti-rat Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

IL-27/IL-35 EBI3 Subunit Antibody (10J811) - NBP2-03941 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 10J811
Western Blot: EBI3 Antibody (10J811) [NBP2-03941] - Western blot testing of mouse EBI3 monoclonal antibody at A) 0.1 ug/ml on recombinant protein and B) 3 ug/ml on recombinant mouse IL-35 protein Goat anti-rat Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

IL-27/IL-35 EBI3 Subunit Antibody (10J706) - NBP2-03938 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 10J706
Western Blot: EBI3 Antibody (10J706) [NBP2-03938] - Western blot testing of mouse EBI3 monoclonal antibody at 0.1 ug/ml on recombinant protein. Goat anti-rat Ig HRP secondary antibody and ECL substrate solution were used for this test.

IL-27/IL-35 EBI3 Subunit Antibody (V1.4F5.25) - NBP2-21640 from Novus Biologicals

Prices $429.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone V1.4F5.25
Blocking/Neutralizing: EBI3 Antibody (V1.4F5.25) [NBP2-21640]

IL-27/IL-35 EBI3 Subunit Antibody (V1.4C4.22) - NBP2-21638 from Novus Biologicals

Prices $429.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone V1.4C4.22
ELISA: EBI3 Antibody (V1.4C4.22) [NBP2-21638] - Supernatant from 293T cells transfected with a vector containing murine IL-35 was added to an ELISA plate coated with V1.4H6.29 at 2ug/ml in PBS. mEBI3 was detected with biotinylated V1.4C4.22

IL-27/IL-35 EBI3 Subunit Antibody (V1.4H6.29) - NBP2-21639 from Novus Biologicals

Prices $429.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone V1.4H6.29
Western Blot: EBI3 Antibody (V1.4H6.29) [NBP2-21639] - Supernatants from cultures containing indicated cells were immunoprecipitated with an anti-p35 mAb plus protein G beads, resolved by SDS page gel and blotted with biotinylated anti mouse EBI-3 clone V1.4H6.29 at 1 ug/ml. The negative and positive controls were supernatants from 293T cells transfected with either vector only or vector containing murine IL-35.

IL-27 Antibody (RM0258-11B29) - NBP2-11704 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone RM0258-11B29

IL-27/IL-35 EBI3 Subunit Antibody (5P10D3) [Alexa Fluor (R) 700] - NBP2-03943AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 5P10D3

IL-27/IL-35 EBI3 Subunit Antibody (5P10D3) [Alexa Fluor (R) 647] - NBP2-03943AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 5P10D3

IL-27/IL-35 EBI3 Subunit Antibody (10J706) [Alexa Fluor (R) 488] - NBP2-03938AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 10J706

IL-27/IL-35 EBI3 Subunit Antibody (10J706) [Alexa Fluor (R) 405] - NBP2-03938AF405 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 10J706

IL-27/IL-35 EBI3 Subunit Antibody (5P6G8) [Alexa Fluor (R) 647] - NBP2-03942AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 5P6G8

IL-27/IL-35 EBI3 Subunit Antibody (5P6G8) [Alexa Fluor (R) 488] - NBP2-03942AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 5P6G8

IL-27/IL-35 EBI3 Subunit Antibody (5P6G8) [Alexa Fluor (R) 405] - NBP2-03942AF405 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 5P6G8

IL-27/IL-35 EBI3 Subunit Antibody (10J811) [Alexa Fluor (R) 700] - NBP2-03941AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 10J811

IL-27/IL-35 EBI3 Subunit Antibody (10J811) [Alexa Fluor (R) 647] - NBP2-03941AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 10J811
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