Ebi3

Gene Symbol	Ebi3
Entrez Gene	50498
Alt Symbol	EBI-3, IL-27
Species	Mouse
Gene Type	protein-coding
Description	Epstein-Barr virus induced gene 3
Other Description	IL-27 subunit beta|IL-27B|epstein-Barr virus-induced gene 3 protein homolog|interleukin-27 subunit beta
Swissprots	O35228
Accessions	EDL23692 EDL23693 O35228 AF013114 AAB67115 AK155023 BAE32996 AK155903 BAE33494 AW495532 BC008209 AAH08209 BI134394 BY134465 CX240802 XM_006524599 XP_006524662 NM_015766 NP_056581
Function	Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T- helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Subcellular Location	Secreted {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-27/IL-35 EBI3 Subunit Recombinant Protein - P4622 from Novus Biologicals Category Protein Prices $549.00 Sizes 10 µg Species Mouse

Recombinant Mouse IL-27/IL-35 EBI3 Subunit Protein - NBP1-99327 from Novus Biologicals Category Protein Prices $185.00 Sizes 20 µg Source E. coli

IL-27/IL-35 EBI3 Subunit Protein - NBP1-99764 from Novus Biologicals Category Protein Species Mouse

EBI3 Protein (OPPA02062) - OPPA02062 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Mouse EBI3 protein - orb139190 from Biorbyt Category Protein Prices $221.00, $400.00, $612.00 Sizes 5 μg, 10 μg, 20 μg Source Human Cells Species Mouse

EBI3 protein - 30R-2594 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli Species Mouse

EBI3 / IL27B - P4622 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Mouse

Epstein Barr Virus Induced 3, Mouse Recombinant - 228-10349-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Mouse

Recombinant Mouse EBI3 - 228-10349-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Mouse

Recombinant Mouse EBI3 - 228-10349-3 from RayBiotech Category Protein Source Escherichia Coli. Species Mouse

EBI3 Mouse - CYPS-628 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Mouse

Mouse EBI-3 - 600178 from ABBIOTEC Category Protein Prices $250.00 Sizes 10 µg Source E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug. Species Mouse

Recombinant Mouse Epstein Barr Virus Induced 3 - BP000074-CYT-621 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Mouse

Recombinant Mouse Epstein Barr Virus Induced 3 - GWB-FBACC2 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Species Mouse

Recombinant Mouse Ebi3&Il27 - Ebi3&Il27-952M from Creative Biomart Category Protein Source NSO Cells Species Mouse

Recombinant Mouse Epstein-Barr Virus Induced Gene 3 - Ebi3-1317M from Creative Biomart Category Protein Source E.coli .

Epstein Barr Virus Induced 3 Mouse - BCA-235 from Reagent Proteins Category Protein Prices $348.00, $5,334.00 Sizes 10.00 µg, 1 mg Source E.coli Species Mouse

IL-35 EBI3 Mouse Recombinant Protein - 010-001-B66 from Rockland Immunochemicals Inc Category Protein Prices $229.00 Sizes 10 µg Species Mouse

EBI-3 - 010-001-C55-0002 from Rockland Immunochemicals Inc Prices $95.00 Sizes 2 µg Species Mouse

EBI-3 - 010-001-C55-0100 from Rockland Immunochemicals Inc Prices $559.00 Sizes 100 µg Species Mouse

EBI-3 - 010-001-C55-1000 from Rockland Immunochemicals Inc Prices $4,800.00 Sizes 1 mg Species Mouse

Recombinant Mouse Interleukin-27 subunit beta(Ebi3) - CSB-YP007360MO CSB-EP007360MO CSB-BP007360MO CSB-MP007360MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

IL-27 / EBI-3, murine recombinant - 4377-100 from Biovision Category Protein Prices $695.00 Sizes 100 μg Source E. coli Species Mouse

IL-27 / EBI-3, murine recombinant - 4377-1000 from Biovision Category Protein Prices $5,200.00 Sizes 1 mg Source E. coli Species Mouse

IL-27 / EBI-3, murine recombinant - 4377-20 from Biovision Category Protein Prices $185.00 Sizes 20 µg Source E. coli Species Mouse

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