PFN1

Gene Symbol	PFN1
Entrez Gene	5216
Alt Symbol	ALS18
Species	Human
Gene Type	protein-coding
Description	profilin 1
Other Description	epididymis tissue protein Li 184a|profilin I|profilin-1
Swissprots	Q53Y44 P07737
Accessions	EAW90381 EAW90382 EAW90383 EAW90384 P07737 AA358044 AK312168 BAG35102 AL525538 BC002475 AAH02475 BC006768 AAH06768 BC013439 AAH13439 BC015164 AAH15164 BC057828 AAH57828 BM850671 BT007001 AAP35647 CR407670 CAG28598 D28377 BAA05743 DQ891100 ABM82026 DQ894282 ABM85208 GU727630 ADU87632 J03191 AAA36486 NM_005022 NP_005013
Function	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. {ECO:0000269|PubMed:18573880}.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}.
Top Pathways	Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PFN1 / Profilin 1 ELISA Kit (Sandwich ELISA) - LS-F6790 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 28 pg/ml Range 78.13-5000 pg/ml

Human PFN1 / Profilin 1 ELISA Kit (Sandwich ELISA) - LS-F12421 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 pg/ml Range 78.13-5000 pg/ml

Human Profilin 1 ELISA Kit - abx152832 from Abbexa Category ELISA Kit Sensitivity 31 pg/ml Range 78.125 pg/ml - 5000 pg/ml

Anti-Profilin 1 antibody, Human, ELISA Kit - CSB-E14969h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Anti-Profilin 1 antibody, Human, ELISA Kit - E01A2112 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Profilin 1 (PFN1), Human, ELISA Kit - SEC233Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 31pg/mL Range 78-5,000pg/mL

Profilin 1, Human, ELISA Kit - CSB-E16491h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.8 pg/ml Range 31.25 pg/ml-2000 pg/ml

Profilin-1, PFN1, Human, ELISA Kit - E2122h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

anti Profilin 1 antibody, ELISA Kit - MBS7209725 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

PFN1, ELISA Kit - MBS2515942 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

Profilin 1, ELISA Kit - MBS097798 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

profilin 1, ELISA Kit - MBS705845 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human profilin is typically less than 7.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml -2000 pg/ml.

Profilin 1, ELISA Kit - MBS088890 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Profilin 1, ELISA Kit - MBS081474 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Profilin 1, ELISA Kit - MBS097667 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Profilin 1, ELISA Kit - MBS060555 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Profilin 1, ELISA Kit - MBS091539 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Profilin 1, ELISA Kit - MBS068831 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Profilin 1 (PFN1), ELISA Kit - MBS2019962 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 28pg/mL. Range 78.13-5000pg/mL

ELISA Kit for Profilin 1 (PFN1) - SEC233Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 28pg/mL. Range 78.13-5000pg/mL The standard curve concentrations used for the ELISA’s were 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312.5pg/mL, 156.25pg/mL, 78.13pg/mL

Human anti-Profilin 1 antibody ELISA Kit - CSB-E14969h from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

Human Profilin 1 ELISA Kit - CSB-E16491h from Cusabio Category ELISA Kit Sensitivity 7.8pg/ml Range 31.25 pg/ml-2000 pg/ml

ELISA Kit for Profilin 1 (PFN1) - SEC233Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 28pg/mL. Range 78.125-5000pg/mL The standard curve concentrations used for the ELISA's were 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312.5pg/mL, 156.25pg/mL, 78.125pg/mL

Rat PFN1 / Profilin 1 ELISA Kit (Custom ELISA) - LS-F19303 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78.13-5000 pg/ml

Mouse PFN1 / Profilin 1 ELISA Kit (Custom ELISA) - LS-F19304 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78.13-5000 pg/ml

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