Stam2

Gene Symbol Stam2
Entrez Gene 56324
Alt Symbol 1200004O12Rik, 5730456G07Rik, BB145015, Hbp
Species Mouse
Gene Type protein-coding
Description signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Other Description Hrs binding protein|STAM-2|hrs-binding protein|signal transducing adapter molecule 2
Swissprots Q8C8Y4 A2AU00 O88811
Accessions AAX90618 CAX15926 EDL26912 EDL26913 O88811 AB012611 BAA33547 AK004604 BAB23403 AK017668 AK035789 AK044230 BAC31830 AK078244 AK159699 BAE35299 AK168729 BAE40570 AK188839 AK214650 BC013818 AAH13818 DQ141211 AAZ82831 XM_006498198 XP_006498261 NM_019667 NP_062641
Function Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10651905, ECO:0000269|PubMed:12551915}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Tissue Specificity Ubiquitously expressed, with highest levels in testis. {ECO:0000269|PubMed:10651905}.
Top Pathways Jak-STAT signaling pathway, Endocytosis

Recombinant Mouse Signal transducing adapter molecule 2(Stam2) - CSB-YP022793MO CSB-EP022793MO CSB-BP022793MO CSB-MP022793MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Signal Transducing Adaptor Molecule 2 (STAM2) - RPC873Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse STAM2 Protein - STAM2-16093M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

STAM2 Recombinant Protein (OPCD07211) - OPCD07211 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Signal transducing adapter molecule 2 (Stam2), Recombinant Protein - MBS1051571 from MyBioSource

Category Protein
Prices $1,315.00, $1,315.00, $1,530.00, $1,530.00, $2,165.00, $2,165.00, $2,630.00, $2,630.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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