CD80

Gene Symbol CD80
Entrez Gene 941
Alt Symbol B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Species Human
Gene Type protein-coding
Description CD80 molecule
Other Description B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
Swissprots P33681 Q5DTB0 Q5DTA9
Accessions AAA58390 AAC51754 ABK41933 EAW79564 EAW79565 P33681 AK292129 BAF84818 AY081815 AAL89819 AY197777 AAO39208 AY197778 AAO39209 BC042665 AAH42665 BP225173 M27533 AAA36045 XM_011513325 XP_011511627 XM_011513326 XP_011511628 XM_011513327 XP_011511629 NM_005191 NP_005182
Function Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269|PubMed:10583602}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed on activated B-cells, macrophages and dendritic cells.
Top Pathways Toll-like receptor signaling pathway, Type I diabetes mellitus, Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease

B7-1 (F-7) - sc-376012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
B7-1 (F-7): sc-376012. Western blot analysis of B7-1 expression in human PBL whole cell lysate.

B7-1 (C-20) - sc-1633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
B7-1 (C-20): sc-1633. Western blot analysis of B7-1 expression in Ramos whole cell lysate.

B7-1 (H-208) - sc-9091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
B7-1 (H-208): sc-9091. Western blot analysis of B7-1 expression in Ramos whole cell lysate.

B7-1 (N-20) - sc-1634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
B7-1 (N-20): sc-1634. Western blot analysis of B7-1 expression in human PBL whole cell lysate.

B7-1 (2D10) - sc-73382 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-CD80 antibody - ab104033 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CD80 antibody (ab104033) at 1/100 dilution + HL60 cell lysate at 35 µg

Anti-CD80 antibody - ab106747 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-CD80 antibody (ab106747) at 1 µg/ml + Human Lymph node lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-CD80 antibody [2A2] - ab86473 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A2
Confocal immunofluorescence analysis of BCBL-1 cells using ab86473 at 1/200 dilution (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.

Anti-CD80 antibody [2D10.4], prediluted (PE/Cy5®) - ab155374 from Abcam

Prices $188.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 2D10.4
Flow Cytometric analysis of normal Human peripheral blood cells labeling CD80 with ab155374 (filled histogram) at 1 µg/test in 100 µl final volume or an equal amount of Mouse IgG1 kappa Isotype Control PE-Cy5 (open histogram). Cells in the lymphocyte gate were used for analysis.

Anti-CD80 antibody [2D10.4] - Low endotoxin, Azide free - ab185742 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2D10.4

Anti-CD80 antibody [EPR1157(2)] - ab134120 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1157(2)
Anti-CD80 antibody [EPR1157(2)] (ab134120) at 1/250 dilution (unpurified) + Raji cell lysate at 20 µgSecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-CD80 antibody [MEM-233] - ab8239 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-233

Anti-CD80 antibody [MEM-233] (Allophycocyanin) - ab27554 from Abcam

Prices $193.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-233
ab27554 staining CD80 in human activated CD19+ B-cells by Flow Cytometery. Sample was prepared in FACS buffer (PBS, 0.5% FCS. 0.5M EDTA) and gating was done on CD19+ B-cells. The primary antibody was used undiluted and incubated with sample for 20 minutes at 4°C. See Abreview

Anti-CD80 antibody [MEM-233] (FITC) - ab18279 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-233

Anti-CD80 antibody [MEM-233] (PerCP) - ab82410 from Abcam

Prices $186.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-233

Anti-CD80 antibody [MEM-233], prediluted (Phycoerythrin) - ab69778 from Abcam

Prices $186.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-233

Anti-CD80 Antibody - LS-C306857 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CD80 Antibody (aa1-224) - LS-C311768 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CD80 Antibody (aa258-288, FITC) - LS-C254133 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD80 Antibody - LS-C309833 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CD80 Antibody (aa258-288) - LS-C320207 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CD80 Antibody (clone 1G1) - LS-C196850 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G1
Detection limit for recombinant GST tagged CD80 is 0.3 ng/ml as a capture antibody.

Anti-CD80 Antibody (clone 2E5) - LS-C115529 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E5
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-CD80 mouse monoclonal antibody.

Anti-CD80 Antibody (aa227-245) - LS-C343886 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CD80 antibody Western blot. All lanes: Anti CD80 at 0.5 ug/ml. WB: Rat Thymus Tissue Lysate at 50 ug. Predicted band size: 34 kD. Observed band size: 50 kD.

Anti-CD80 Antibody (clone 3F1) - LS-C172390 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3F1
IHC of paraffin-embedded Human lymphoma tissue using anti-CD80 mouse monoclonal antibody.
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