CD80

Gene Symbol CD80
Entrez Gene 941
Alt Symbol B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Species Human
Gene Type protein-coding
Description CD80 molecule
Other Description B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
Swissprots P33681 Q5DTB0 Q5DTA9
Accessions AAA58390 AAC51754 ABK41933 EAW79564 EAW79565 P33681 AK292129 BAF84818 AY081815 AAL89819 AY197777 AAO39208 AY197778 AAO39209 BC042665 AAH42665 BP225173 M27533 AAA36045 XM_011513325 XP_011511627 XM_011513326 XP_011511628 XM_011513327 XP_011511629 NM_005191 NP_005182
Function Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269|PubMed:10583602}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed on activated B-cells, macrophages and dendritic cells.
Top Pathways Toll-like receptor signaling pathway, Type I diabetes mellitus, Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease

B7-1 CRISPR/Cas9 KO Plasmid (h) - sc-401971 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 HDR Plasmid (h) - sc-401971-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 Double Nickase Plasmid (h) - sc-401971-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 Double Nickase Plasmid (h2) - sc-401971-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 CRISPR Activation Plasmid (h) - sc-401971-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 CRISPR Activation Plasmid (h2) - sc-401971-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 Lentiviral Activation Particles (h) - sc-401971-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 Lentiviral Activation Particles (h2) - sc-401971-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

B7-1 siRNA (h) - sc-29773 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

B7-1 shRNA Plasmid (h) - sc-29773-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

B7-1 shRNA (h) Lentiviral Particles - sc-29773-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU036201 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5752 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5752 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CD80 siRNA (Human) - CRH0663 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

B7-1/CD80 RNAi - H00000941-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CD80 - MBS8221807 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD80 (NM_005191.3) - SHH259377 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CD80(NM_005191.3) - SHG159145 from Creative biogene

Category siRNA
Species Reactivities Human

Human CD80 siRNA - orb261165 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD80 shRNA Plasmid (Human) - CHH0663 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CD80 miRNA 3'UTR clone - MiUTR1H-01908 from Creative biogene

Species Reactivities Human
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