CD80

Gene Symbol	CD80
Entrez Gene	941
Alt Symbol	B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Species	Human
Gene Type	protein-coding
Description	CD80 molecule
Other Description	B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
Swissprots	P33681 Q5DTB0 Q5DTA9
Accessions	AAA58390 AAC51754 ABK41933 EAW79564 EAW79565 P33681 AK292129 BAF84818 AY081815 AAL89819 AY197777 AAO39208 AY197778 AAO39209 BC042665 AAH42665 BP225173 M27533 AAA36045 XM_011513325 XP_011511627 XM_011513326 XP_011511628 XM_011513327 XP_011511629 NM_005191 NP_005182
Function	Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269|PubMed:10583602}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed on activated B-cells, macrophages and dendritic cells.
Top Pathways	Toll-like receptor signaling pathway, Type I diabetes mellitus, Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD80 Lysate(Denatured) - H00000941-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

B7-1/CD80 Overexpression Lysate (Denatured) - H00000941-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

B7-1/CD80 Overexpression Lysate (Native) - NBP2-07780 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

B7-1 (h): 293T Lysate - sc-115617 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Cynomolgus CD80 / B7-1 HEK293 Cell Lysate (WB positive control) - 90268-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Cynomolgus CD80 / B7-1 HEK293 Cell Lysate (WB positive control) - 90268-C02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human CD80 / B7-1 HEK293 Cell Lysate (WB positive control) - 10698-HCCHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD80 / B7-1 HEK293 Cell Lysate (WB positive control) - 10698-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD80 / B7-1 HEK293 Cell Lysate (WB positive control) - 10698-H03HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human B7-1 Human Cells Transfected Lysate (positive control) (denatured) - orb173132 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human B7-1 Human Cells Transfected Lysate (positive control) (denatured) - orb172781 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human B7-1 Human Cells Transfected Lysate (positive control) (denatured) - orb172782 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human CD80 Knockdown Stable Cell Line - CSC-DC002773 from Creative biogene Category Cell Line Species Human

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