HMGCR

Gene Symbol	HMGCR
Entrez Gene	3156
Alt Symbol	LDLCQ3
Species	Human
Gene Type	protein-coding
Description	3-hydroxy-3-methylglutaryl-CoA reductase
Other Description	3-hydroxy-3-methylglutaryl CoA reductase (NADPH)|3-hydroxy-3-methylglutaryl-Coenzyme A reductase|HMG-CoA reductase|hydroxymethylglutaryl-CoA reductase
Swissprots	B7Z3Y9 Q8N190 P04035
Accessions	AAG21343 AAP72015 CAZ64465 EAW95754 EAW95755 EAW95756 P04035 AA648735 AK292892 BAF85581 AK296499 BAH12375 AK299655 BAG61573 AK312437 BAG35346 AY429541 AY429542 AY429543 BC024180 BC033692 AAH33692 CN278665 DQ890855 ABM81781 DQ894009 ABM84935 M11058 AAA52679 M62627 M62633 XM_011543357 XP_011541659 XM_011543358 XP_011541660 XM_011543359 XP_011541661 NM_000859 NP_000850 NM_001130996 NP_001124468
Function	Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways	Terpenoid backbone biosynthesis, Bile secretion, AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HMGCR peptide - ab107787 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human HMGCR full length protein - ab132810 from Abcam Category Protein Source Wheat germ Species Human

HMG-CoA Reductase / HMGCR Antibody Blocking Peptide - LS-E26911 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMGCR-Antibody-Center-Blocking-Peptide - BP6577c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HMGCR blocking peptide - GTX88456-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant human 3-hydroxy-3-methylglutaryl-coenzyme A reductase (OPCA00118) - OPCA00118 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human HMGCR protein - orb244273 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

HMGCR Immunizing peptide - orb55109 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

HMGCR Peptide - AC21-1743-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

HMG-CoA reductase / HMGCR - H00003156-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

HMGCR Peptide - 42-049P from ProSci Category Peptide

HMGCR Peptide - PM-7211P from ProSci Category Peptide Species Human

HMGCR fusion protein - ag4444 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human HMGCR - HMGCR-231H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) - RPD686Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant human 3-hydroxy-3-methylglutaryl-coenzyme A reductase - CSB-YP010565HU CSB-BP010565HU CSB-MP010565HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human 3-hydroxy-3-methylglutaryl-coenzyme A reductase - CSB-EP010565HU from Cusabio Category Protein Source E.coli Species Human

HMG-CoA Reductase Catalytic Domain (GST Tagged), human recombinant - 7841-100 from Biovision Category Protein Prices $85.00 Sizes 100 μg Source E. coli Species Human

HMG-CoA Reductase Catalytic Domain (GST Tagged), human recombinant - 7841-500 from Biovision Category Protein Prices $325.00 Sizes 500 μg Source E. coli Species Human

HMG-CoA Blocking Peptide - 3952BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 μg

3-hydroxy-3-methylglutaryl-coenzyme A reductase - RPC140026 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

3-hydroxy-3-methylglutaryl-coenzyme A reductase, Recombinant Protein - MBS1156525 from MyBioSource Category Protein Prices $2,275.00, $2,735.00 Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell

3-hydroxy-3-methylglutaryl-coenzyme A reductase, Recombinant Protein - MBS1103804 from MyBioSource Category Protein Prices $2,880.00, $3,335.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell

3-hydroxy-3-methylglutaryl-coenzyme A reductase, Recombinant Protein - MBS947962 from MyBioSource Category Protein Prices $110.00, $285.00, $460.00, $490.00, $750.00, $835.00, $975.00, $1,120.00, $1,180.00, $1,220.00, $1,230.00, $1,265.00, $1,775.00, $1,845.00, $1,925.00, $2,360.00 Sizes 10 µg (E-Coli), 100 µg (E-Coli), 200 µg (E-Coli), 50 µg (E-Coli), 500 µg (E-Coli), 50 µg (Yeast), 50 µg (Baculovirus), 200 µg (Yeast), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 500 µg (Yeast), 500 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

3-hydroxy-3-methylglutaryl-coenzyme A reductase, Recombinant Protein - MBS1145855 from MyBioSource Category Protein Prices $3,090.00, $3,550.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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