Tlr7

Gene Symbol Tlr7
Entrez Gene 170743
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description toll-like receptor 7
Other Description -
Swissprots Q923I1 P58681
Accessions AGX25544 AGX25545 AGX25546 AGX25547 AGX25548 EDL40709 P58681 AF334942 AAL73191 AF334943 AAL73192 AJ812652 CAH25327 AJ812654 CAH25329 AK036549 BAC29472 AK154906 BAE32916 AK156908 BAE33892 AK172680 BAE43127 AY035889 AAK62676 BC120596 AAI20597 BC132385 AAI32386 BY204351 BY543663 XM_006528713 XP_006528776 XM_011247785 XP_011246087 XM_011247786 XP_011246088 NM_001290755 NP_001277684 NM_001290756 NP_001277685 NM_001290757 NP_001277686 NM_001290758 NP_001277687 NM_133211 NP_573474
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:14976261}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:18305481}; Single-pass type I membrane protein {ECO:0000269|PubMed:18305481}. Endosome {ECO:0000269|PubMed:18305481}. Lysosome {ECO:0000269|PubMed:18305481}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:18305481}. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Top Pathways Toll-like receptor signaling pathway, Measles, Influenza A

TLR7 Antibody (726606) - MAB7156 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 726606
Western blot shows lysates of mouse thymus tissue and NR8383 rat alveolar macrophage cell line. PVDF membrane was probed with 1 µg/mL of Rat Anti-Mouse/Rat TLR7 Monoclonal Antibody (Catalog # MAB7156) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody. A specific band was detected for TLR7 at approximately 130 to 140 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

TLR7 Antibody - NB100-80844 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: TLR7 Antibody [NB100-80844] - Staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ANTI-MOUSE TLR7 (C-TERM) antibody produced in rabbit - SAB1305053 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Mouse Tlr7 (N-term) antibody produced in rabbit - SAB1300204 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal

Anti-Mouse Tlr7 (C-term) antibody produced in rabbit - SAB1300205 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-mouse TLR7 (C-term) Antibody: <B>Cat. No. SAB1300205</B>: mouse TLR7 in human breast carcinoma tissue with Anti-mouse TLR7 (C-term) Antibody at 40 μg/mL.

Anti-TLR7 antibody produced in rabbit - PRS3269 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunocytochemistry</B><BR/>Anti-TLR7: <B>Cat. No. PRS3269</B> Immunocytochemistry staining of Daudi cells using TLR7 antibody at 2 μg/mL.

Toll-Like Receptor 7 Antibody - abx116126 from Abbexa

Host Rabbit
Clonality Polyclonal

Toll-like receptor 7 Antibody - abx110268 from Abbexa

Host Rabbit
Clonality Polyclonal

Toll-like receptor 7 Antibody (Biotin) - abx105978 from Abbexa

Host Rabbit
Clonality Polyclonal

Toll-like receptor 7 Antibody (FITC) - abx107393 from Abbexa

Host Rabbit
Clonality Polyclonal

Toll-like receptor 7 Antibody (HRP) - abx108813 from Abbexa

Host Rabbit
Clonality Polyclonal

TLR7 antibody - AP09155PU-N from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot using IgG fraction of anti-TLR7 antibody shows detection of a predominant band at ~121 kDa corresponding to TLR7 (arrowhead) in a Daudi whole cell lysate. The predicted MW of TLR7 is 121 kDa. TLR7 was detected using 0.5 µg/ml (lane A), 1.0 µg/ml (lane B) and 2 µg/ml (lane C) concentrations of primary antibody.

TLR7 (Center) antibody - AP30905PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry staining of Daudi cells using AP30905PU-N at 2 μg/ml.

TLR7 antibody - PAB9788 from Acris Antibodies

Prices $430.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Tlr7 expression in Daudi cell lysates with Tlr7 polyclonal antibody ( Cat # PAB9788 ) at 2 µg/ml.

TLR7 antibody - PAB11332 from Acris Antibodies

Prices $580.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot using Tlr7 polyclonal antibody ( Cat # PAB11332 ) shows detection of a predominant band at ~121 kDa corresponding to Tlr7 ( arrowhead ) in a Daudi whole cell lysate. The predicted MW of Tlr7 is 121 kDa. Tlr7 was detected using 0.5 µg/ml ( lane A ) , 1.0 µg/ml ( lane B ) and 2 µg/ml ( lane C ) concentrations of primary antibody.

TLR7 Antibody - 3269 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TLR7 in Daudi cell lysates with TLR7 antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.

TLR7, Polyclonal Antibody - MBS150192 from MyBioSource

Prices $140.00, $355.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TLR7 Antibody - 253470 from ABBIOTEC

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TLR7 Antibody - 24228 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of TLR7 in Daudi cell lysates with TLR7 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.

BD Pharmingen™ PE Mouse Anti-Mouse TLR7 (CD287) - 565557 from BD Biosciences

Prices $225.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone A94B10

TLR7 (clone 4F4), Antibody - GWB-3C55C8 from Genway Biotech

Prices $185.00, $310.00
Sizes 50 μl, 100 μl
Host Mouse
Clonality Monoclonal
Clone Anti-human TLR7 mAb, clone 4F4, is derived fr

Anti-Toll-like Receptor 7 (TLR7) Antibody - GWB-558381 from Genway Biotech

Prices $415.00
Sizes 100 µg
Host Rabbit

TLR7 Antibody - TGB-907 from Reagent Proteins

Prices $348.00, $675.00
Sizes 20.00 µg, 100.00 µg
Host Mouse
Clonality Monoclonal

Anti-TLR7 polyclonal antibody - CPBT-65293RM from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Rabbit anti-human TLR7 Polyclonal antibody - DPAB-L21300 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal
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