Gene Symbol | Tlr7 |
---|---|
Entrez Gene | 170743 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | toll-like receptor 7 |
Other Description | - |
Swissprots | Q923I1 P58681 |
Accessions | AGX25544 AGX25545 AGX25546 AGX25547 AGX25548 EDL40709 P58681 AF334942 AAL73191 AF334943 AAL73192 AJ812652 CAH25327 AJ812654 CAH25329 AK036549 BAC29472 AK154906 BAE32916 AK156908 BAE33892 AK172680 BAE43127 AY035889 AAK62676 BC120596 AAI20597 BC132385 AAI32386 BY204351 BY543663 XM_006528713 XP_006528776 XM_011247785 XP_011246087 XM_011247786 XP_011246088 NM_001290755 NP_001277684 NM_001290756 NP_001277685 NM_001290757 NP_001277686 NM_001290758 NP_001277687 NM_133211 NP_573474 |
Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:14976261}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18305481}; Single-pass type I membrane protein {ECO:0000269|PubMed:18305481}. Endosome {ECO:0000269|PubMed:18305481}. Lysosome {ECO:0000269|PubMed:18305481}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:18305481}. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. |
Top Pathways | Toll-like receptor signaling pathway, Measles, Influenza A |
Toll Like Receptor 7 (TLR7), Mouse, ELISA Kit - SEB950Mu from ARP American Research Products
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Toll-like receptor 7, Tlr7, Mouse, ELISA Kit - E1950m from ARP American Research Products
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toll-like receptor 7, ELISA Kit - MBS704084 from MyBioSource
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Mouse Toll-like receptor 7,TLR-7 ELISA Kit - CSB-E14341m from Cusabio
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Toll Like Receptor 7 (TLR7), Mouse, ELISA Kit - DL-TLR7-Mu from ARP American Research Products
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Mouse TLR7(Toll Like Receptor 7) ELISA Kit - E-EL-M2695 from Elabscience
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Mouse TLR7 ELISA Kit - abx570416 from Abbexa
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Mouse Toll-like receptor 7 ELISA Kit - EKE53379 from Biomatik
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Mouse Tlr7 ELISA Kit - E070359 from Biobool
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Mouse TLR-7 ELISA Kit - E070361 from Biobool
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TLR7 ELISA Kit (Mouse) (OKEH03430) - OKEH03430 from Aviva Systems Biology
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Mouse Toll-like receptor 7 ELISA Kit - EK4116 from Signalway Antibody
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Toll Like Receptor 7 (TLR7), ELISA Kit - MBS455493 from MyBioSource
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Toll-like receptor 7, ELISA Kit - MBS2883660 from MyBioSource
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Toll-like receptor 7, ELISA Kit - MBS9427945 from MyBioSource
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Mouse TLR7 ELISA Kit - orb408868 from Biorbyt
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