Tlr7

Gene Symbol	Tlr7
Entrez Gene	170743
Alt Symbol	-
Species	Mouse
Gene Type	protein-coding
Description	toll-like receptor 7
Other Description	-
Swissprots	Q923I1 P58681
Accessions	AGX25544 AGX25545 AGX25546 AGX25547 AGX25548 EDL40709 P58681 AF334942 AAL73191 AF334943 AAL73192 AJ812652 CAH25327 AJ812654 CAH25329 AK036549 BAC29472 AK154906 BAE32916 AK156908 BAE33892 AK172680 BAE43127 AY035889 AAK62676 BC120596 AAI20597 BC132385 AAI32386 BY204351 BY543663 XM_006528713 XP_006528776 XM_011247785 XP_011246087 XM_011247786 XP_011246088 NM_001290755 NP_001277684 NM_001290756 NP_001277685 NM_001290757 NP_001277686 NM_001290758 NP_001277687 NM_133211 NP_573474
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:14976261}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:18305481}; Single-pass type I membrane protein {ECO:0000269|PubMed:18305481}. Endosome {ECO:0000269|PubMed:18305481}. Lysosome {ECO:0000269|PubMed:18305481}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:18305481}. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Top Pathways	Toll-like receptor signaling pathway, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse TLR7 gene - orb91974 from Biorbyt Prices $264.00 Sizes 10 μg Species Mouse

Mouse Tlr7 ORF Clone(NM_133211.3) - CDCL178610 from Creative Biomart Species Mouse Accession NM_133211.3

Mouse Tlr7 ORF Clone(NM_133211.3) - CDCR265080 from Creative Biomart Species Mouse Accession NM_133211.3

Mouse Tlr7 ORF Clone(NM_133211.3) - CDCR265081 from Creative Biomart Species Mouse Accession NM_133211.3

Mouse Tlr7 ORF clone - CDCH091456 from Creative Biomart Species Mouse Accession NM_133211

Mouse Tlr7 ORF clone - CDCH091457 from Creative Biomart Species Mouse Accession NM_133211

Mouse TLR7 ORF clone(NM_133211.3) - CDCG001186 from Creative Biomart Species Mouse Accession NM_133211.3

Mouse TLR7 ORF clone(NM_133211.3) - CDCL186483 from Creative Biomart Species Mouse Accession NM_133211.3

Mouse TLR7 Gene ORF cDNA clone in cloning vector - MG50962-G from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, C-Flag tag - MG50962-CF from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG50962-ACR from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, N-Myc tag - MG50962-NM from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, C-Myc tag - MG50962-CM from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, C-His tag - MG50962-CH from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, C-HA tag - MG50962-CY from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, N-His tag - MG50962-NH from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG50962-ACG from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid - MG50962-UT from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, N-HA tag - MG50962-NY from Sino Biological Species Mouse

Mouse TLR7 Gene ORF cDNA clone expression plasmid, N-Flag tag - MG50962-NF from Sino Biological Species Mouse

Mouse TLR7 ORF clone(NM_133211.3) - CDCL186483 from Creative biogene Species Mouse

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